Reid M M, Malcolm A J, McGuckin A G
Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne.
J Clin Pathol. 1990 Apr;43(4):334-6. doi: 10.1136/jcp.43.4.334.
Frozen sections from bone marrow trephine biopsy specimens from children with disseminated neuroblastoma were stained using the monoclonal antibody UJ13A. An immunoalkaline phosphatase technique was the preferred staining method. Acceptable histological detail was obtained from this material and deposits of tumour cells detected. Some apparently fibrous tissue was also stained by this antibody. The results show that this immunohistological approach is feasible and provide encouragement for its addition to the range of investigations currently available for assessing the marrows of children with this disease.
使用单克隆抗体UJ13A对患有播散性神经母细胞瘤儿童的骨髓环钻活检标本的冰冻切片进行染色。免疫碱性磷酸酶技术是首选的染色方法。从该材料中获得了可接受的组织学细节，并检测到肿瘤细胞沉积。一些明显的纤维组织也被该抗体染色。结果表明，这种免疫组织学方法是可行的，并为将其添加到目前用于评估患有这种疾病儿童骨髓的一系列检查中提供了依据。
