Centre for Medical Psychology and Evidence-based Decision-making (CeMPED); School of Psychology, The University of Sydney, Sydney, NSW, Australia.
Int J Behav Med. 2012 Dec;19(4):518-25. doi: 10.1007/s12529-011-9182-5.
Human papillomavirus (HPV) is a common sexually transmitted infection (STI) known to cause cervical cancer and genital warts. However, making the genital warts aspect explicit may reduce HPV vaccination intention and behaviour due to perceived stigma associated with STIs.
This study investigated the effect of differential information framing on intention to receive the HPV vaccine using the Theory of Planned Behaviour (TPB) and moral norm construct.
Female university students were randomised to receive a fact sheet describing the HPV vaccine as: (1) preventing cervical cancer only (n = 81); or (2) preventing both cervical cancer and genital warts (n = 78). A 2-month follow-up investigated relationships between vaccination intention and actual behaviour.
No effect of information framing was detected on intention to receive the HPV vaccine, or vaccine uptake behaviour at 2-month follow-up. The traditional TPB components predicted 54% of the variance in vaccination intention (F (3,155) = 61.580, p < 0.001), and moral norm explained an additional 6.2%. Intention predicted a significant but relatively small proportion of variation (9.6%) in behaviour.
The HPV vaccine does not seem to be associated with perceptions of stigma related to genital warts, and has broad acceptance among a female university population. This study demonstrates that TPB is suited to investigate HPV vaccination, and has helped clarify the role of moral norm within the TPB.
人乳头瘤病毒（HPV）是一种常见的性传播感染（STI），已知可导致宫颈癌和生殖器疣。然而，由于与 STI 相关的污名化感知，明确生殖器疣方面可能会降低 HPV 疫苗接种的意愿和行为。
本研究使用计划行为理论（TPB）和道德规范构建来调查差异化信息框架对 HPV 疫苗接种意愿的影响。
随机将女大学生分为两组，分别接受描述 HPV 疫苗的情况说明书：（1）仅预防宫颈癌（n=81）；或（2）同时预防宫颈癌和生殖器疣（n=78）。在 2 个月的随访中，调查了疫苗接种意愿与实际行为之间的关系。
信息框架对 HPV 疫苗接种意愿或 2 个月随访时的疫苗接种行为没有影响。传统的 TPB 成分预测了接种意愿的 54%（F(3,155)=61.580，p<0.001），道德规范解释了另外的 6.2%。意愿预测了行为的显著但相对较小的变化（9.6%）。
HPV 疫苗似乎与生殖器疣相关的污名化感知无关，并且在女大学生群体中得到广泛接受。本研究表明 TPB 适合于研究 HPV 疫苗接种，并且有助于澄清道德规范在 TPB 中的作用。
