Rodu B, Tate A L, Martinez M G
Department of Pathology, University of Alabama School of Medicine, Birmingham.
J Oral Pathol. 1987 Nov;16(10):518-21. doi: 10.1111/j.1600-0714.1987.tb00684.x.
The histologic features of 112 odontogenic keratocysts (OKC's) were examined from both a clinical and histopathological perspective with emphasis on the microscopic presence of inflammation and its relationship to transformation of the classic epithelial cyst lining found in OKC's to a nonkeratinized lining characteristic of common inflammatory odontogenic cysts. Eighty-five (76%) of these cases exhibited inflammation. The sensitivity of inflammation as a predictor of this aforementioned transformation is 100%, and its positive predictive value is 88%. The specificity of the same parameters remains high at 73%. Using previous studies, the implications of these findings on the biologic behavior of OKC's is discussed with special reference to therapeutic considerations.
从临床和组织病理学角度对112例牙源性角化囊肿（OKC）的组织学特征进行了检查，重点关注炎症的微观表现及其与OKC中典型上皮囊肿衬里转变为常见炎性牙源性囊肿的非角化衬里特征之间的关系。其中85例（76%）出现炎症。炎症作为上述转变预测指标的敏感性为100%，其阳性预测值为88%。相同参数的特异性仍高达73%。结合以往研究，特别参考治疗方面的考虑，讨论了这些发现对OKC生物学行为的影响。
