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减轻负担?基于社区药店的体重管理干预措施的系统评价。

Lightening the load? A systematic review of community pharmacy-based weight management interventions.

机构信息

Community Dietetic Department, Westholme, Woodend Hospital, Aberdeen, UK.

出版信息

Obes Rev. 2011 Nov;12(11):897-911. doi: 10.1111/j.1467-789X.2011.00913.x. Epub 2011 Aug 25.

Abstract

The extent to which community pharmacies can increase capacity for weight management is unknown. Thus, the objective of the present paper was to evaluate the effectiveness and cost-effectiveness of community pharmacy weight management interventions. This paper used a design of systematic review and narrative synthesis. Electronic databases (1999-2009) were searched, including Medline, EMBASE, CINAHL and Pharm-line. Weight management studies in community pharmacies were eligible for the inclusion criteria. All languages and study designs were considered. Outcome measures included body weight or anthropometry (at baseline and at least one follow-up time point). Data were extracted through independent, duplicate data extraction and quality assessment. As a result, 10 studies were included, totalling 2,583 service users and 582 pharmacies from the USA, the UK, Switzerland, Spain and Denmark. One was a randomized controlled trial of a meal-replacement versus a reduced calorie diet. A non-randomized controlled before and after study compared community pharmacist treatment using Orlistat with usual care. Eight studies were uncontrolled. Five studies described behaviour change techniques. Long-term (12 months) mean weight loss measured in three studies ranged from 1.1 to 4.1 kg. Four uncontrolled studies reported statistically significant weight loss. No study reported economic evaluations. Currently, there is insufficient evidence for the effectiveness and cost-effectiveness of community pharmacy-based weight management initiatives to support investment in their provision.

摘要

社区药房增加体重管理能力的程度尚不清楚。因此,本研究旨在评估社区药房体重管理干预措施的效果和成本效益。本文采用系统评价和叙述性综合的设计。检索了电子数据库(1999-2009 年),包括 Medline、EMBASE、CINAHL 和 Pharm-line。符合纳入标准的社区药房体重管理研究包括在内。考虑了所有语言和研究设计。结果测量包括体重或人体测量学(在基线和至少一个随访时间点)。通过独立、重复的数据提取和质量评估来提取数据。结果,共纳入 10 项研究,来自美国、英国、瑞士、西班牙和丹麦的 2583 名服务用户和 582 家药店。其中一项是代餐与低热量饮食的随机对照试验。一项使用奥利司他的社区药剂师治疗与常规护理的非随机对照前后研究进行了比较。八项研究为非对照研究。五项研究描述了行为改变技术。三项研究中,长期(12 个月)体重减轻的平均值从 1.1 到 4.1 公斤不等。四项非对照研究报告了统计学上显著的体重减轻。没有研究报告经济评估。目前,社区药房体重管理计划的有效性和成本效益证据不足,不足以支持对其提供的投资。

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