Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina, USA.
Clin Transl Sci. 2011 Aug;4(4):259-65. doi: 10.1111/j.1752-8062.2011.00310.x.
This project aimed to develop an open-access website providing adaptable resources to facilitate best practices for multisite research from initiation to closeout. methods: A web-based assessment was sent to the leadership of the Clinical and Translational Science Award (CTSA) Community Engagement Key Functions Committee (n= 38) and the CTSA-affiliated Primary Care Practice-based Research Networks (PBRN, n= 55). Respondents rated the benefits and barriers of multisite research, the utility of available resources, and indicated their level of interest in unavailable resources. Then, existing research resources were evaluated for relevance to multisite research, adaptability to other projects, and source credibility.
Fifty-five (59%) of invited participants completed the survey. Top perceived benefits of multisite research were the ability to conduct community-relevant research through academic-community partnerships (34%) and accelerating translation of research into practice (31%). Top perceived barriers were lack of research infrastructure to support PBRNs and community partners (31%) and inadequate funding to support multisite collaborations (26%). Over 200 resources were evaluated, of which 120 unique resources were included in the website.
The PRIMER Research Toolkit (http://www.researchtoolkit.org) provides an array of peer-reviewed resources to facilitate translational research for the conduct of multisite studies within PBRNs and community-based organizations.
本项目旨在开发一个开放获取的网站,提供可适应的资源,以促进从启动到关闭的多站点研究的最佳实践。
对临床和转化科学奖(CTSA)社区参与关键功能委员会(n=38)和 CTSA 附属初级保健实践为基础的研究网络(PBRN,n=55)的领导层发送了基于网络的评估。受访者对多站点研究的益处和障碍、现有资源的实用性以及对不可用资源的兴趣程度进行了评分。然后,对现有的研究资源进行了相关性、对其他项目的适应性和来源可信度的评估。
55 名(59%)受邀参与者完成了调查。多站点研究的最大益处是通过学术-社区伙伴关系进行与社区相关的研究的能力(34%)和加速研究转化为实践的能力(31%)。最大的障碍是缺乏支持 PBRN 和社区合作伙伴的研究基础设施(31%)以及支持多站点合作的资金不足(26%)。评估了 200 多个资源,其中包括 120 个独特的资源,这些资源被纳入了该网站。
PRIMER 研究工具包(http://www.researchtoolkit.org)提供了一系列经过同行评审的资源,以促进 PBRN 和基于社区的组织内进行多站点研究的转化研究。