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模仿恶性淋巴增殖性疾病的急性传染性单核细胞增多症的免疫表型特征：一例报告并文献复习

Immunophenotypic profile in acute infectious mononucleosis mimicking malignant lymphoproliferative disorder: a case report and review of literature.

作者信息

Tembhare Prashant, Ramani Manisha, Syed Keerti, Gupta Amar Das

机构信息

Hematology, Coagulation and Flow Cytometry, Super Religare Laboratories Ltd, Mumbai, India.

出版信息

Indian J Hematol Blood Transfus. 2010 Sep;26(3):118-21. doi: 10.1007/s12288-010-0041-3. Epub 2010 Sep 30.

DOI:10.1007/s12288-010-0041-3
PMID:21886400
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3002080/
Abstract

Infectious mononucleosis is characterized by an intensive lymphoproliferation with atypical forms which sometimes resemble with acute leukemia or malignant lymphoproliferative diseases. Flow cytometric analysis of lymphocytes shows a typical phenotype but unawareness of it may lead to misdiagnosis of malignant lymphoproliferative diseases. Herewith we present an immunophenotypic profile in a case of acute infectious mononucleosis and review of literature.

摘要

传染性单核细胞增多症的特征是伴有非典型形态的强烈淋巴细胞增殖，这些非典型形态有时类似于急性白血病或恶性淋巴细胞增殖性疾病。淋巴细胞的流式细胞术分析显示出典型的表型，但对此缺乏认识可能导致恶性淋巴细胞增殖性疾病的误诊。在此，我们展示一例急性传染性单核细胞增多症的免疫表型特征并进行文献复习。

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本文引用的文献

1
Flow cytometric immunophenotyping for hematologic neoplasms.血液系统肿瘤的流式细胞术免疫表型分析
Blood. 2008 Apr 15;111(8):3941-67. doi: 10.1182/blood-2007-11-120535. Epub 2008 Jan 15.
2
Massive expansion of EBV+ monoclonal T cells with CD5 down regulation in EBV-associated haemophagocytic lymphohistiocytosis.在EB病毒相关噬血细胞性淋巴组织细胞增生症中，EB病毒阳性单克隆T细胞大量扩增并伴有CD5下调。
J Clin Pathol. 2007 Jan;60(1):101-3. doi: 10.1136/jcp.2005.034371.
3
Increasing incidence of severe Epstein-Barr virus-related infectious mononucleosis: surveillance study.严重的爱泼斯坦-巴尔病毒相关传染性单核细胞增多症发病率上升：监测研究
J Clin Microbiol. 2006 May;44(5):1873-4. doi: 10.1128/JCM.44.5.1873-1874.2006.
4
Center for Disease Control (CDC) flow cytometry panel for human immunodeficiency virus infection allows recognition of infectious mononucleosis caused by Epstein-Barr virus or cytomegalovirus.美国疾病控制与预防中心（CDC）用于人类免疫缺陷病毒感染的流式细胞术检测板可识别由爱泼斯坦-巴尔病毒或巨细胞病毒引起的传染性单核细胞增多症。
Croat Med J. 2003 Dec;44(6):702-6.
5
Rapid turnover of T cells in acute infectious mononucleosis.急性传染性单核细胞增多症中T细胞的快速更新。
Eur J Immunol. 2003 Oct;33(10):2655-65. doi: 10.1002/eji.200324295.
6
Comparative immunophenotypic features of EBV-positive and EBV-negative atypical lymphocytosis.EBV 阳性和 EBV 阴性非典型淋巴细胞增多症的比较免疫表型特征
Cytometry B Clin Cytom. 2003 Sep;55(1):22-8. doi: 10.1002/cyto.b.10043.
7
Down-regulation of pan-T-cell antigens, particularly CD7, in acute infectious mononucleosis.急性传染性单核细胞增多症中泛T细胞抗原尤其是CD7的下调。
Am J Clin Pathol. 2003 Jul;120(1):49-55. doi: 10.1309/VC7M-24UC-5VG7-EUEC.
8
An approach to diagnosis of T-cell lymphoproliferative disorders by flow cytometry.一种通过流式细胞术诊断T细胞淋巴增殖性疾病的方法。
Cytometry. 2002 Jun 15;50(3):177-90. doi: 10.1002/cyto.10003.
9
Immunophenotypic analysis of peripheral T-cell neoplasms. A multiparameter flow cytometric approach.外周T细胞肿瘤的免疫表型分析。一种多参数流式细胞术方法。
Am J Clin Pathol. 2001 Oct;116(4):512-26. doi: 10.1309/QF6N-VAQW-N74H-4JE2.
10
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Clin Exp Immunol. 2000 May;120(2):294-300. doi: 10.1046/j.1365-2249.2000.01181.x.