寡糖合成的反向正交策略。
Reverse orthogonal strategy for oligosaccharide synthesis.
机构信息
Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.
出版信息
Chem Commun (Camb). 2011 Oct 14;47(38):10602-4. doi: 10.1039/c1cc13409d. Epub 2011 Sep 5.
Abstract
Herein, we report the invention of a novel expeditious concept for oligosaccharide synthesis. Unlike the classic orthogonal strategy based on leaving groups, the reverse approach is based on orthogonal protecting groups, herein p-methoxybenzyl and 4-pentenoyl, which allows for efficient oligosaccharide assembly in the reverse direction.
摘要
在此，我们报告了一种新颖的寡糖合成策略。与基于离去基团的经典正交策略不同，该反方向策略基于正交保护基，即 p-甲氧基苄基和 4-戊烯酰基，这使得在反方向上能够有效地进行寡糖组装。
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