Department of Gynecology and Obstetrics, Atrium Medical Center, Parkstad, The Netherlands.
J Perinat Med. 2011 Sep;39(5):539-43. doi: 10.1515/jpm.2011.054.
To determine the inter- and intra-observer variation of volume calculations of human fetuses at a gestational age of 11(+0)-13(+6) weeks by three-dimensional ultrasound (3DUS).
3DUS datasets were acquired during nuchal translucency measurements. The fetal volume (FV) was measured in 65 cases by two independent investigators. The Virtual Organ Computer aided AnaLysis (VOCAL™) imaging software was used to manually calculate the FV (rotational angle 9°). Inter- and intra-observer variation were assessed by Bland-Altman plots and intraclass correlation coefficients (ICC).
Both inter- and intraobserver reproducibility were highly reliable as shown by the Bland-Altman plots and an ICC of respectively 0.934 and 0.994.
FV calculation by 3DUS with VOCAL and a rotational angle of 9° is feasible and has a high inter- and intraobserver reliability in the first trimester of pregnancy.
通过三维超声（3DUS）确定 11（+0）-13（+6）孕周胎儿体积计算的观察者内和观察者间变异。
在颈项透明层测量期间获取 3DUS 数据集。两名独立的研究者在 65 例中测量了胎儿体积（FV）。使用虚拟器官计算机辅助分析（VOCAL™）成像软件手动计算 FV（旋转角度 9°）。通过 Bland-Altman 图和组内相关系数（ICC）评估观察者内和观察者间的变异。
Bland-Altman 图和 ICC 分别为 0.934 和 0.994，均显示出观察者内和观察者间的重现性均高度可靠。
使用 VOCAL 和 9°旋转角度的 3DUS 进行 FV 计算在妊娠早期具有可行性，且观察者内和观察者间的可靠性高。
