Segagni Daniele, Tibollo Valentina, Dagliati Arianna, Perinati Leonardo, Zambelli Alberto, Priori Silvia, Bellazzi Riccardo
IRCCS Fondazione S. Maugeri, Pavia, Italy.
Stud Health Technol Inform. 2011;169:887-91.
The University of Pavia and the IRCCS Fondazione Salvatore Maugeri of Pavia (FSM), has recently started an IT initiative to support clinical research in oncology, called ONCO-i2b2. ONCO-i2b2, funded by the Lombardia region, grounds on the software developed by the Informatics for Integrating Biology and the Bedside (i2b2) NIH project. Using i2b2 and new software modules purposely designed, data coming from multiple sources are integrated and jointly queried. The core of the integration process stands in retrieving and merging data from the biobank management software and from the FSM hospital information system. The integration process is based on a ontology of the problem domain and on open-source software integration modules. A Natural Language Processing module has been implemented, too. This module automatically extracts clinical information of oncology patients from unstructured medical records. The system currently manages more than two thousands patients and will be further implemented and improved in the next two years.
帕维亚大学和帕维亚的IRCCS萨尔瓦托雷·毛杰里基金会（FSM）最近启动了一项信息技术计划，以支持肿瘤学临床研究，名为ONCO-i2b2。ONCO-i2b2由伦巴第大区资助，基于美国国立卫生研究院（NIH）的整合生物学与床边信息学（i2b2）项目开发的软件。使用i2b2和专门设计的新软件模块，可以整合来自多个来源的数据并进行联合查询。整合过程的核心在于从生物样本库管理软件和FSM医院信息系统中检索和合并数据。整合过程基于问题领域的本体论和开源软件集成模块。还实施了一个自然语言处理模块。该模块可从非结构化医疗记录中自动提取肿瘤患者的临床信息。该系统目前管理着两千多名患者，并将在未来两年内进一步实施和改进。
