Department of Renal Medicine, Derby Hospitals NHS Foundation Trust, Derby, UK.
BMC Nephrol. 2012 Jun 8;13:33. doi: 10.1186/1471-2369-13-33.
The extent and the distribution of end stage kidney disease (ESKD) in Libya have not been reported despite provision of dialysis over 4 decades. This study aimed to develop the first comprehensive description of the epidemiology of dialysis-treated ESKD in Libya.
Structured demographic and clinical data were obtained regarding all adult patients treated at all maintenance dialysis facilities (n=39) in Libya from May to September 2009. Subsequently data were collected prospectively on all new patients who started dialysis from September 2009 to August 2010. Population estimates were obtained from the Libyan national statistics department. The age and gender breakdown of the population in each region was obtained from mid-2009 population estimates based on 2006 census data.
The prevalence of dialysis-treated ESKD was 624 per million population (pmp). 85% of prevalent patients were aged <65 years and 58% were male. The prevalence of ESKD varied considerably with age with a peak at 55-64 years (2475 pmp for males; 2197 pmp for females). The annual incidence rate was 282 pmp with some regional variation and a substantially higher rate in the South (617 pmp). The most common cause of ESKD among prevalent and incident patients was diabetes. Other important causes were glomerulonephritis, hypertensive nephropathy and congenital or hereditary diseases.
Libya has a relatively high prevalence and incidence of dialysis-treated ESKD. As the country prepares to redevelop its healthcare system it is hoped that these data will guide strategies for the prevention of CKD and planning for the provision of renal replacement therapy.
尽管利比亚已经提供了 40 多年的透析治疗，但仍未报告终末期肾病（ESKD）的范围和分布情况。本研究旨在首次全面描述利比亚透析治疗 ESKD 的流行病学情况。
2009 年 5 月至 9 月，从利比亚所有维持性透析机构（n=39）中获得了有关所有成年患者的结构化人口统计学和临床数据。随后，从 2009 年 9 月至 2010 年 8 月开始，前瞻性地收集了所有开始透析的新患者的数据。人口估计数来自利比亚国家统计局。根据 2006 年人口普查数据，从 2009 年年中人口估计数中获得了每个地区的人口年龄和性别分布情况。
透析治疗 ESKD 的患病率为 624/百万人（pmp）。85%的现患患者年龄<65 岁，58%为男性。ESKD 的患病率随年龄变化很大，在 55-64 岁之间达到高峰（男性为 2475 pmp；女性为 2197 pmp）。年发病率为 282 pmp，存在一定的区域差异，南部发病率较高（617 pmp）。现患和新发病例中 ESKD 的最常见原因是糖尿病。其他重要原因包括肾小球肾炎、高血压肾病和先天性或遗传性疾病。
利比亚透析治疗 ESKD 的患病率和发病率相对较高。随着该国准备重新发展其医疗保健系统，希望这些数据将为预防 CKD 和规划肾脏替代治疗提供指导策略。
