College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325027, PR China.
Org Lett. 2011 Oct 7;13(19):5004-7. doi: 10.1021/ol201713b. Epub 2011 Sep 7.
A simple copper-mediated cyanation of aryl halide with the combination of ammonium bicarbonate and N,N-dimethylformamide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical and safe method for the synthesis of aryl nitriles.
一种简单的铜介导的芳基卤化物与碳酸氢铵和 N,N-二甲基甲酰胺的组合的氰化反应，实现了腈的中等至良好收率。这种新方法为芳基腈的合成提供了一种极其实用和安全的方法。
