天然产物中的Sepbox技术。
Sepbox technique in natural products.
作者信息
Bhandari M, Bhandari Anil, Bhandari A
机构信息
Department of Pharmacognosy, Jodhpur College of Pharmacy, Jodhpur National University, Jodhpur, India.
出版信息
J Young Pharm. 2011 Jul;3(3):226-31. doi: 10.4103/0975-1483.83771.
Natural compounds still play an increasingly important role in many areas of research and development. Their structural diversity is enhanced by the synthetic potential of combinatorial chemistry. Fractionation and separation of samples obtained from nature remain time-consuming, tedious and extremely expensive even though the assays for testing these samples have become faster and more cost-effective thanks to advanced high-throughput screening (HTS) processes. Today, sepbox is the standard technology used for separating compounds from natural resources. Fractionations and separation of samples obtained from nature remain very difficult. Automation of sample preparation therefore has great economic potential. The unique sepbox concept allows processing sample automatically and will make up to 30 times faster than by using a conventional process.
天然化合物在许多研发领域仍发挥着越来越重要的作用。组合化学的合成潜力增强了它们的结构多样性。尽管由于先进的高通量筛选（HTS）技术，测试这些从自然界获取的样品的分析方法变得更快且更具成本效益，但对这些样品进行分馏和分离仍然耗时、繁琐且极其昂贵。如今，Sepbox是用于从自然资源中分离化合物的标准技术。从自然界获取的样品的分馏和分离仍然非常困难。因此，样品制备的自动化具有巨大的经济潜力。独特的Sepbox概念允许自动处理样品，其速度比使用传统方法快30倍。
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