Gleason Jonathan Lee, Markland Alayne, Greer Wm Jerod, Szychowski Jeff M, Gerten Kimberly A, Richter Holly E
Division of Women's Pelvic Medicine and Reconstructive Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Int Urogynecol J. 2011 Dec;22(12):1587-92. doi: 10.1007/s00192-011-1551-8. Epub 2011 Sep 6.
The objective of this study was to determine the effect of external anal sphincter repair on fecal incontinence symptoms, quality of life, and anal sphincter squeeze pressures.
The fecal incontinence symptoms and impact on quality of life, patient satisfaction, and anorectal manometry were assessed pre- and post-operatively.
One hundred four women were eligible and 74/104 (71%) returned post-operative questionnaires. Fifty-four of 74 (73%) had pre- and post-operative questionnaires. Twenty-five of 74 (34%) had pre- and post-operative anorectal manometry measures. Mean length of follow-up for participants (n = 54) was 32 ± 19 months. Modified Manchester Health Questionnaire scores decreased from 47.3 ± 21.9 to 28.4 ± 24.3 (p < 0.01) and Fecal Incontinence Severity Index scores from 30.6 ± 13.0 to 21.6 ± 15.5 (p < 0.01). Seventy-seven percent of the participants was satisfied. Sphincter squeeze pressures increased from 53.4 ± 25.0 to 71.8 ± 29.1 mmHg (p < 0.01).
External anal sphincter repair resulted in sustained improvements in fecal incontinence severity and quality of life along with improved anal sphincter squeeze pressures.
本研究的目的是确定肛门外括约肌修复对大便失禁症状、生活质量和肛门括约肌收缩压的影响。
在手术前后评估大便失禁症状及其对生活质量的影响、患者满意度和肛肠测压。
104名女性符合条件，74/104（71%）返回了术后问卷。74名中有54名（73%）有术前和术后问卷。74名中有25名（34%）有术前和术后肛肠测压测量。参与者（n = 54）的平均随访时间为32±19个月。改良曼彻斯特健康问卷评分从47.3±21.9降至28.4±24.3（p < 0.01），大便失禁严重程度指数评分从30.6±13.0降至21.6±15.5（p < 0.01）。77%的参与者表示满意。括约肌收缩压从53.4±25.0 mmHg升至71.8±29.1 mmHg（p < 0.01）。
肛门外括约肌修复使大便失禁严重程度和生活质量得到持续改善，同时肛门括约肌收缩压也有所提高。
