Ma Jun, Ba Hua-jie, Zhang Wen-jie, Li Kai
Detachment Criminal of Public Security Bureau of Changzhou, Changzhou, Jiangsu, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Aug;33(4):397-401. doi: 10.3881/j.issn.1000-503X.2011.04.010.
To investigate the polymorphism of 17 short tandem repeat (STR) loci of Tibetan minority ethnic group from Lhasa.
Blood samples were obtained from 132 unrelated Tibetan individuals from Lhasa. DNA templates were screened by home-made AGCU17+1 kit and 3130XL genetic analyzer. Genotyping was performed using GeneMapper software (version 3.2).
The allele frequencies of 17 STR loci ranged 0.0038-0.5720, and the power of discrimination ranged 0.779-0.979, the power of exclusion ranged 0.327-0.737, the polymorphism information contents ranged 0.538-0.910, and the heterozygosity ranged 0.629-0.871. The cumulative coupling probability was 3.93 × 10(-20), and the cumulative power of exclusion was 0.9999995234. Of 17 STR loci, Penta E and D6S1043 had the highest polymorphism indicators, while TPOX had the lowest.
The 17 STR loci used in this study are highly polymorphism in Tibetan minority ethnic group from Lhasa and fit for the population genetic study and forensic cases.
