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用于未来患者护理的生物样本库资源:发展、原则与概念

Biobank resources for future patient care: developments, principles and concepts.

作者信息

Végvári Akos, Welinder Charlotte, Lindberg Henrik, Fehniger Thomas E, Marko-Varga György

机构信息

Clinical Protein Science & Imaging, Biomedical Center, Dept, of Measurement Technology and Industrial Electrical Engineering, Lund University, BMC C13, SE-221 84 Lund, Sweden.

出版信息

J Clin Bioinforma. 2011 Sep 16;1(1):24. doi: 10.1186/2043-9113-1-24.

DOI:10.1186/2043-9113-1-24
PMID:21923917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3197484/
Abstract

The aim of the overview is to give a perspective of global biobank development is given in a view of positioning biobanking as a key resource for healthcare to identify new potential markers that can be used in patient diagnosis and complement the targeted personalized drug treatment. The fast progression of biobanks around the world is becoming an important resource for society where the patient benefit is in the focus, with a high degree of personal integrity and ethical standard. Biobanks are providing patient benefits by large scale screening studies, generating large database repositories. It is envisioned by all participating stakeholders that the biobank initiatives will become the future gateway to discover new frontiers within life science and patient care. There is a great importance of biobank establishment globally, as biobanks has been identified as a key area for development in order to speed up the discovery and development of new drugs and protein biomarker diagnostics. One of the major objectives in Europe is to establish concerted actions, where biobank networks are being developed in order to combine and have the opportunity to share and build new science and understanding from complex disease biology. These networks are currently building bridges to facilitate the establishments of best practice and standardizations.

摘要

本综述的目的是从将生物样本库定位为医疗保健的关键资源的角度,给出全球生物样本库发展的一个视角,以识别可用于患者诊断并补充靶向个性化药物治疗的新潜在标志物。世界各地生物样本库的快速发展正成为社会的一项重要资源,其中患者受益是重点,同时具备高度的个人隐私保护和道德标准。生物样本库通过大规模筛查研究提供患者受益,生成大型数据库存储库。所有参与的利益相关者都设想,生物样本库计划将成为发现生命科学和患者护理新前沿的未来之门。全球建立生物样本库非常重要,因为生物样本库已被确定为一个关键发展领域,以加速新药和蛋白质生物标志物诊断的发现与开发。欧洲的主要目标之一是采取协调行动,目前正在建立生物样本库网络,以便结合并获得分享和从复杂疾病生物学建立新科学及理解的机会。这些网络目前正在搭建桥梁,以促进最佳实践和标准化的建立。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5d1/3197484/f9ec45066ca4/2043-9113-1-24-6.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5d1/3197484/6f2569a323ee/2043-9113-1-24-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5d1/3197484/970441d21384/2043-9113-1-24-2.jpg
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