一个偶然的发现：镍催化剂用于二炔与未活化腈的环加成反应。
A serendipitous discovery: nickel catalyst for the cycloaddition of diynes with unactivated nitriles.
机构信息
Department of Chemistry, University of Utah, 315 South, 1400 East, Salt Lake City, UT 84112-0850, USA.
出版信息
Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10694-8. doi: 10.1002/anie.201104475. Epub 2011 Sep 20.
Abstract
The catalytic combination of Ni(COD) and Xantphos was used to access pyridines. The reaction proceeds under ambient conditions to provide excellent yields of products. Comparison of this catalyst with the other state-of-the-art catalysts is also provided.
摘要
采用 Ni(COD) 和 Xantphos 的催化组合来合成吡啶。该反应在环境条件下进行，可获得优异的产物收率。还提供了该催化剂与其他最先进的催化剂的比较。
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