Radiation Physics Department, Queen's Centre for Oncology and Haematology, Castle Hill Hospital, Hull & East Yorkshire Hospitals, Castle Road, Hull, UK.
Br J Radiol. 2011 Oct;84(1006):890-902. doi: 10.1259/bjr/30125639.
The purpose of this study was to develop and validate a computer model to produce realistic simulated computed radiography (CR) chest images using CT data sets of real patients.
Anatomical noise, which is the limiting factor in determining pathology in chest radiography, is realistically simulated by the CT data, and frequency-dependent noise has been added post-digitally reconstructed radiograph (DRR) generation to simulate exposure reduction. Realistic scatter and scatter fractions were measured in images of a chest phantom acquired on the CR system simulated by the computer model and added post-DRR calculation.
The model has been validated with a phantom and patients and shown to provide predictions of signal-to-noise ratios (SNRs), tissue-to-rib ratios (TRRs: a measure of soft tissue pixel value to that of rib) and pixel value histograms that lie within the range of values measured with patients and the phantom. The maximum difference in measured SNR to that calculated was 10%. TRR values differed by a maximum of 1.3%.
Experienced image evaluators have responded positively to the DRR images, are satisfied they contain adequate anatomical features and have deemed them clinically acceptable. Therefore, the computer model can be used by image evaluators to grade chest images presented at different tube potentials and doses in order to optimise image quality and patient dose for clinical CR chest radiographs without the need for repeat patient exposures.
本研究旨在开发和验证一种计算机模型,使用真实患者的 CT 数据集生成逼真的模拟计算机放射摄影(CR)胸部图像。
通过 CT 数据真实模拟了限制胸部放射摄影中病理学检测的解剖噪声,并且在数字重建放射图(DRR)生成后添加了频率相关噪声,以模拟曝光减少。在通过计算机模型模拟的 CR 系统获得的胸部体模图像中测量了逼真的散射和散射分数,并在 DRR 计算后添加。
该模型已经过体模和患者的验证,能够提供信噪比(SNR)、组织与肋骨比(TRR:软组织像素值与肋骨像素值之比)和像素值直方图的预测值,这些预测值在患者和体模测量值的范围内。测量 SNR 与计算 SNR 的最大差异为 10%。TRR 值的最大差异为 1.3%。
有经验的图像评估者对 DRR 图像反应积极,对其包含足够的解剖特征感到满意,并认为它们具有临床可接受性。因此,图像评估者可以使用计算机模型对不同管电压和剂量下呈现的胸部图像进行分级,以优化临床 CR 胸部射线照片的图像质量和患者剂量,而无需对患者进行重复曝光。