Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Addiction. 2012 Mar;107(3):567-77. doi: 10.1111/j.1360-0443.2011.03662.x.
Depressive symptomatology can increase risk of development of alcohol problems in young people. Tension reduction and family interactional theories may explain the relationship between depression and problematic alcohol use in youth. This study addresses the nature of the longitudinal relationship between these two behaviours. The available literature is currently inconclusive about whether there are gender differences in these relationships; this is also examined.
The association between childhood depressive behaviours and adolescence problematic alcohol use was examined using ordered logistic regression models. Evidence of gender differences and the impact of relevant covariates on these relations were examined. Missing data were imputed using a Multiple Imputation by Chained Equation (MICE) approach.
The Avon Longitudinal Study of Parents and Children (ALSPAC), a large UK population-based birth cohort.
A total of 4220 British boys and girls.
Depressive symptomatology was assessed in childhood (mean age = 10.6, SD = 0.2) using the Short Mood and Feelings Questionnaire (SMFQ). Problematic alcohol use was assessed from several questions queried in adolescence (mean age = 13.8, SD = 0.2).
Childhood depressive symptoms were associated with increased risk of problematic alcohol use in early adolescence for girls [odds ratio (OR) = 1.14, P = 0.016] but not boys. This association for girls weakened (OR = 1.12, P = 0.058) when a priori selected covariates were taken into account, particularly the family and greater social environment.
Problematic alcohol use in girls (but not boys) is associated with prior depressive symptoms. This association may be attributable to several family and social environment factors, suggesting that a family interactional theoretical model may explain these findings.
抑郁症状可能会增加年轻人出现酒精问题的风险。紧张缓解和家庭相互作用理论可能解释了青少年抑郁和酗酒问题之间的关系。本研究探讨了这两种行为之间的纵向关系的本质。目前，关于这些关系是否存在性别差异，相关文献尚无定论，本研究也对此进行了探讨。
使用有序逻辑回归模型检验儿童期抑郁行为与青春期酗酒问题之间的关联。检验了性别差异的证据以及这些关系中相关协变量的影响。使用链式方程多重插补（MICE）方法对缺失数据进行了插补。
阿冯纵向研究父母和儿童（ALSPAC），这是一个基于英国人口的大型出生队列。
共有 4220 名英国男孩和女孩。
使用短期情绪和感觉问卷（SMFQ）在儿童期评估抑郁症状（平均年龄= 10.6，SD= 0.2）。从青春期询问的几个问题评估了酗酒问题（平均年龄= 13.8，SD= 0.2）。
对于女孩，儿童期的抑郁症状与青春期早期酗酒问题的风险增加相关（比值比[OR] = 1.14，P = 0.016），但对于男孩则没有。当考虑到预先选择的协变量时，这种女孩的关联减弱（OR = 1.12，P = 0.058），特别是家庭和更大的社会环境。
对于女孩（而不是男孩），酗酒问题与先前的抑郁症状有关。这种关联可能归因于几个家庭和社会环境因素，这表明家庭相互作用理论模型可以解释这些发现。
