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比较 INNO-LiPA 和 PapType 检测方法在存档外阴发育不良和/或肿瘤组织活检标本中检测人乳头瘤病毒的效果。

Comparison of the INNO-LiPA and PapType assays for detection of human papillomavirus in archival vulva dysplasia and/or neoplasia tissue biopsy specimens.

机构信息

Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Victoria 3052, Australia.

出版信息

J Clin Microbiol. 2011 Nov;49(11):3980-2. doi: 10.1128/JCM.00516-11. Epub 2011 Sep 21.

DOI:10.1128/JCM.00516-11
PMID:21940480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3209107/
Abstract

INNO-LiPA and PapType human papillomavirus (HPV) genotyping assays were compared for detection of HPV genotypes on archival vulvar tissue. The INNO-LiPA assay detected 49 HPV-16 infections, compared with 47 detected by the PapType assay. The INNO-LiPA assay detected amplifiable DNA in 59 (91%) biopsy specimens, compared with 57 (88%) specimens for which amplifiable DNA was detected by the PapType assay. The two genotyping assays were highly comparable.

摘要

INNO-LiPA 和 PapType 人乳头瘤病毒(HPV)基因分型检测方法在检测存档外阴组织中的 HPV 基因型方面进行了比较。INNO-LiPA 检测方法检测到 49 例 HPV-16 感染,而 PapType 检测方法检测到 47 例。INNO-LiPA 检测方法可在 59 例(91%)活检标本中检测到可扩增 DNA,而 PapType 检测方法可在 57 例(88%)标本中检测到可扩增 DNA。两种基因分型检测方法具有高度可比性。

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本文引用的文献

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Human papillomavirus genotyping using archival vulval dysplastic or neoplastic biopsy tissues: comparison between the INNO-LiPA and linear array assays.应用存档外阴发育不良或肿瘤性活检组织进行人乳头瘤病毒基因分型:INNO-LiPA 与线性阵列分析法的比较。
J Clin Microbiol. 2010 Apr;48(4):1458-60. doi: 10.1128/JCM.02311-09. Epub 2010 Feb 24.
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Sustained efficacy and immunogenicity of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine: analysis of a randomised placebo-controlled trial up to 6.4 years.HPV-16/18 AS04 佐剂疫苗的持续疗效和免疫原性:长达 6.4 年的随机安慰剂对照试验分析。
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Human papillomavirus type-distribution in vulvar and vaginal cancers and their associated precursors.人乳头瘤病毒在外阴癌和阴道癌及其相关前驱病变中的型别分布
Obstet Gynecol. 2009 Apr;113(4):917-924. doi: 10.1097/AOG.0b013e31819bd6e0.
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Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis.外阴、阴道和肛门癌及上皮内瘤变中人乳头瘤病毒的患病率和类型分布:一项荟萃分析
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