Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia.
J Clin Microbiol. 2010 Apr;48(4):1458-60. doi: 10.1128/JCM.02311-09. Epub 2010 Feb 24.
The Roche Linear Array (LA) and Innogenetics INNO-LiPA human papillomavirus (HPV) genotyping assays were compared for paraffin-embedded vulval tissues. The LA detected amplifiable DNA in 28 (57%) out of 49 biopsy specimens, 20 (40%) being HPV genotyped, compared to 49 (100%) and 41 (83%), respectively, detected by the INNO-LiPA. The INNO-LiPA provides greater sensitivity for HPV genotyping in archival tissue.
罗氏线性阵列(LA)和 Innogenetics INNO-LiPA 人乳头瘤病毒(HPV)基因分型检测方法用于比较石蜡包埋的外阴组织。LA 在 49 个活检标本中检测到可扩增的 DNA 28 个(57%),20 个(40%)进行了 HPV 基因分型,而 INNO-LiPA 分别检测到 49 个(100%)和 41 个(83%)。INNO-LiPA 在外存档组织中进行 HPV 基因分型时具有更高的敏感性。