Department of Cardiology, Sorgun State Hospital, Yozgat, Turkey.
Angiology. 2012 Jul;63(5):353-7. doi: 10.1177/0003319711420131. Epub 2011 Sep 22.
Mean platelet volume (MPV) is an indicator of platelet activation. We investigated the acute effect of passive smoking on MPV in healthy volunteers. Healthy nonsmoker volunteers (n = 90) spent 120 minutes in a smoke-free room. Then they were exposed to passive smoking in 3 groups consisting of 30 volunteers each in group A (carbon monoxide [CO] < 7.5 ppm), group B (CO = 7.5-15 ppm), and group C (CO > 15 ppm) for 120 minutes in a smoking room. Mean platelet volume did not change in group A and in the smoke-free room. Mean platelet volume increased significantly at the 60th minute and continued to increase at the 90th and 120th minute in group B. Mean platelet volume increased significantly at the 30th minute and continued to increase at the 60th, 90th, and 120th minute in group C. In conclusion, acute exposure to passive smoking affected MPV according to the duration and intensity of smoke.
平均血小板体积（MPV）是血小板活化的一个指标。我们研究了健康志愿者被动吸烟对 MPV 的急性影响。90 名健康不吸烟者志愿者在无烟房间内度过 120 分钟。然后，他们在吸烟室内分别暴露于 3 组，每组 30 名志愿者：A 组（一氧化碳 [CO] < 7.5 ppm）、B 组（CO = 7.5-15 ppm）和 C 组（CO > 15 ppm），每组暴露 120 分钟。A 组和无烟室内的平均血小板体积没有变化。B 组的平均血小板体积在第 60 分钟显著增加，并在第 90 分钟和第 120 分钟继续增加。C 组的平均血小板体积在第 30 分钟显著增加，并在第 60 分钟、第 90 分钟和第 120 分钟继续增加。总之，急性被动吸烟暴露会根据烟雾的持续时间和强度影响 MPV。
