Department of Cardiology, Etlik Ihtisas Research and Education Hospital, Ankara, Turkey.
Angiology. 2012 Aug;63(6):472-5. doi: 10.1177/0003319711422433. Epub 2011 Sep 22.
We evaluated the association of serum uric acid (SUA) level and development of coronary collateral vessels (CCVs) in patients with acute coronary syndrome (ACS). Patients (n = 224) with ACS were included in the study. Coronary collateral vessels were graded according to the Rentrop scoring system. Rentrop grade 0 was accepted as absence of CCV (group 1; n = 117) and Rentrop grade ≥1 was accepted as presence of CCV (group 2; n = 107). Rentrop 0-1 (poor CCV) were determined in 167 patients and Rentrop 2-3 (good CCV) were determined in 57 patients. Both presence of CCV (P < .001) and development of good CCV (P = .003) were significantly associated with low levels of SUA. We suggest that high levels of SUA affect the CCV development negatively in nondiabetic and nonhypertensive patients with ACS.
我们评估了急性冠脉综合征（ACS）患者血清尿酸（SUA）水平与冠状动脉侧支循环（CCV）发展之间的关系。本研究纳入了 224 例 ACS 患者。根据 Rentrop 评分系统对冠状动脉侧支循环进行分级。Rentrop 分级 0 被认为无 CCV（组 1；n=117），Rentrop 分级≥1 被认为有 CCV（组 2；n=107）。167 例患者为 Rentrop 0-1（差的 CCV），57 例患者为 Rentrop 2-3（好的 CCV）。CCV 的存在（P<0.001）和良好 CCV 的发展（P=0.003）均与低水平的 SUA 显著相关。我们认为，在非糖尿病和非高血压 ACS 患者中，高水平的 SUA 可能会对 CCV 的发展产生负面影响。
