Kayseri Research and Education Hospital, Kayseri, Turkey.
J Cardiol. 2013 Apr;61(4):295-8. doi: 10.1016/j.jjcc.2012.12.011. Epub 2013 Mar 6.
Elevated mean platelet volume (MPV) has been proposed as a risk factor for coronary artery disease (CAD) and is associated with poor clinical outcome in acute coronary syndrome (ACS). We aimed to evaluate the association of MPV with presence of coronary collateral vessel (CCV) in patients with ACS.
A total of 417 patients with ACS were included in the study. All patients underwent coronary angiography on the first day after admission and patients with a greater than or equal to 80% obstruction in at least one epicardial coronary artery were included in the study. The CCVs are graded according to the Rentrop scoring system and a Rentrop grade 0 was accepted as no CCV development (group 1), Rentrop grade 1-2-3 were accepted as presence of CCV development (group 2).
The median of MPV was 9.1±1.4fl. Mean age was 60±12 year. Group 1 consisted of 233 (55.9%) patients and Group 2 consisted of 184 (44.1%) patients. Presence of CCV was significantly associated with high levels of MPV (p=0.005). Presence of CCV was also associated with presence of diabetes and systolic blood pressure.
High MPV on admission was associated with presence of CCV in patients with ACS.
平均血小板体积（MPV）升高已被提出作为冠状动脉疾病（CAD）的危险因素，并与急性冠状动脉综合征（ACS）的不良临床结局相关。我们旨在评估 ACS 患者中 MPV 与冠状动脉侧支血管（CCV）存在的相关性。
本研究纳入了 417 名 ACS 患者。所有患者在入院后第一天接受冠状动脉造影，至少一条心外膜冠状动脉存在大于或等于 80%阻塞的患者被纳入研究。CCV 根据 Rentrop 评分系统进行分级，Rentrop 分级 0 被认为是没有 CCV 发育（第 1 组），Rentrop 分级 1-2-3 被认为是存在 CCV 发育（第 2 组）。
MPV 的中位数为 9.1±1.4fl。平均年龄为 60±12 岁。第 1 组包括 233 名（55.9%）患者，第 2 组包括 184 名（44.1%）患者。CCV 的存在与 MPV 水平升高显著相关（p=0.005）。CCV 的存在还与糖尿病和收缩压相关。
ACS 患者入院时 MPV 升高与 CCV 的存在相关。
