Laboratory of Molecular Genetics of Microrganims, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
J Bacteriol. 2011 Oct;193(20):5877-8. doi: 10.1128/JB.05643-11.
Vibrio cholerae O1 Amazonia is a pathogen that was isolated from cholera-like diarrhea cases in at least two countries, Brazil and Ghana. Based on multilocus sequence analysis, this lineage belongs to a distinct profile compared to strains from El Tor and classical biotypes. The genomic analysis revealed that it contains Vibrio pathogenicity island 2 and a set of genes related to pathogenesis and fitness, such as the type VI secretion system, present in choleragenic V. cholerae strains.
霍乱弧菌 O1 亚马逊菌株是一种病原体,它从至少两个国家(巴西和加纳)的霍乱样腹泻病例中分离出来。基于多位点序列分析,与埃尔托和古典生物型菌株相比,该谱系属于一个截然不同的特征。基因组分析显示,它包含霍乱弧菌毒力岛 2 和一组与发病机制和适应性相关的基因,如存在于产毒性霍乱弧菌菌株中的 VI 型分泌系统。