Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Genome Med. 2011 Sep 28;3(9):60. doi: 10.1186/gm276.
The Wellcome Trust Sanger Institute has a strong reputation for prepublication data sharing as a result of its policy of rapid release of genome sequence data and particularly through its contribution to the Human Genome Project. The practicalities of broad data sharing remain largely uncharted, especially to cover the wide range of data types currently produced by genomic studies and to adequately address ethical issues. This paper describes the processes and challenges involved in implementing a data sharing policy on an institute-wide scale. This includes questions of governance, practical aspects of applying principles to diverse experimental contexts, building enabling systems and infrastructure, incentives and collaborative issues.
威康信托桑格研究所因快速发布基因组序列数据的政策而享有发表前数据共享的良好声誉，特别是通过其对人类基因组计划的贡献。广泛数据共享的实际操作在很大程度上仍未得到探索，特别是要涵盖基因组研究目前产生的广泛数据类型，并充分解决伦理问题。本文介绍了在全院范围内实施数据共享政策所涉及的流程和挑战。这包括治理问题、将原则应用于不同实验环境的实际方面、构建支持系统和基础设施、激励措施和合作问题。
