Universidad Peruana Cayetano Heredia, San Martin de Porres, Lima, Peru.
Trans R Soc Trop Med Hyg. 2011 Dec;105(12):734-6. doi: 10.1016/j.trstmh.2011.08.009. Epub 2011 Oct 2.
Norovirus was detected in 17.4% of 224 diarrhoeal samples from children younger than 24 months of age in Lima, in whom all common pathogens had been excluded (pathogen negative). Norovirus was identified more frequently in children older than 12 months of age than in younger children (34% vs 8%, P<0.001). Among norovirus-positive samples, genogroup II was the predominant group (92%). Compared with rotavirus, norovirus episodes tended to be of shorter duration and less severe. The role of norovirus as a cause of diarrhoea and the ascertainment of its severity in developing countries needs further confirmation by future epidemiological studies.
在利马，对 24 个月以下的腹泻儿童（所有常见病原体均已排除（病原体阴性））的 224 个样本进行检测，发现 17.4%的样本中存在诺如病毒。年龄大于 12 个月的儿童中诺如病毒的检出率高于年龄较小的儿童（34%比 8%，P<0.001）。在诺如病毒阳性样本中，Ⅱ型为主要基因型（92%）。与轮状病毒相比，诺如病毒感染的持续时间更短，病情也较轻。诺如病毒作为腹泻病因的作用及其在发展中国家严重程度的确定，需要未来的流行病学研究进一步证实。
