Department of International Health, Johns Hopkins School of Public Health, Baltimore, MD, USA.
Pediatr Infect Dis J. 2009 Sep;28(9):844-7. doi: 10.1097/INF.0b013e3181a24730.
To determine the burden of norovirus infections in children stools from a longitudinal community cohort were evaluated using reverse transcription polymerase chain reaction. Norovirus was detected in 21.3% of diarrheal and 8.0% of nondiarrheal stools (P < 0.01). Norovirus diarrhea was highly associated with age and the odds ratio for norovirus diarrhea fell by 2.8% per month (OR = 0.97, 95% CI: 0.95-0.99). Norovirus seems to be an important etiology of community acquired diarrhea in this study population.
采用逆转录聚合酶链反应（RT-PCR）对纵向社区队列中儿童粪便中的诺如病毒感染负担进行了评估。在腹泻粪便和非腹泻粪便中分别检测到 21.3%和 8.0%的诺如病毒（P<0.01）。诺如病毒腹泻与年龄高度相关，且诺如病毒腹泻的优势比每月下降 2.8%（OR=0.97，95%CI：0.95-0.99）。在本研究人群中，诺如病毒似乎是社区获得性腹泻的重要病因。
