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诺如病毒在秘鲁亚马逊地区儿童中高度流行,是地方性急性腹泻的主要病因。

Norovirus highly prevalent cause of endemic acute diarrhea in children in the peruvian Amazon.

机构信息

Department of International Health, Johns Hopkins School of Public Health, Baltimore, MD, USA.

出版信息

Pediatr Infect Dis J. 2009 Sep;28(9):844-7. doi: 10.1097/INF.0b013e3181a24730.

Abstract

To determine the burden of norovirus infections in children stools from a longitudinal community cohort were evaluated using reverse transcription polymerase chain reaction. Norovirus was detected in 21.3% of diarrheal and 8.0% of nondiarrheal stools (P < 0.01). Norovirus diarrhea was highly associated with age and the odds ratio for norovirus diarrhea fell by 2.8% per month (OR = 0.97, 95% CI: 0.95-0.99). Norovirus seems to be an important etiology of community acquired diarrhea in this study population.

摘要

采用逆转录聚合酶链反应(RT-PCR)对纵向社区队列中儿童粪便中的诺如病毒感染负担进行了评估。在腹泻粪便和非腹泻粪便中分别检测到 21.3%和 8.0%的诺如病毒(P<0.01)。诺如病毒腹泻与年龄高度相关,且诺如病毒腹泻的优势比每月下降 2.8%(OR=0.97,95%CI:0.95-0.99)。在本研究人群中,诺如病毒似乎是社区获得性腹泻的重要病因。

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