Kennedy Philip
Neural Signals Inc., Suite D402, 3400 McClure Bridge Road, Duluth, GA 30096, USA.
Neurocase. 2011 Oct;17(5):381-93. doi: 10.1080/13554794.2010.532137.
In many brain areas, modulations in neuronal firing rates are thought to code information. However, in electrophysiological recording experiments, especially recordings in human patients, the type of information that is coded by a neuron's discharge patterns is often not known, or difficult to determine. From our long experience with chronic recordings in humans, we have come to suspect that such unexplained modulations in firing rates are often due to state changes in the subject. We here present two case studies, with extensive data in one subject to illustrate the point that a change in the subject's emotions, such as sudden fear, surprise, or happiness, may trigger substantial changes in firing rates.
在许多脑区，神经元放电频率的调制被认为是对信息进行编码。然而，在电生理记录实验中，尤其是在人类患者身上进行的记录，由神经元放电模式编码的信息类型往往是未知的，或者难以确定。基于我们在人类慢性记录方面的长期经验，我们开始怀疑这种放电频率中无法解释的调制往往是由于受试者的状态变化。我们在此展示两个案例研究，其中一个受试者有大量数据，以说明受试者情绪的变化，如突然的恐惧、惊讶或喜悦，可能会引发放电频率的显著变化。
