Fisher E R, Palekar A S, Kotwal N, Lipana N
Am J Clin Pathol. 1979 Mar;71(3):240-6. doi: 10.1093/ajcp/71.3.240.
A histological study of 15 examples of a unique proliferative and tubular lesion (Fenoglio and Lattes) of the breast was performed. Although it consistently lacked infiltration of adipose tissue, the commonality of some of its morphologic features and those of tubular cancer provokes the possibility that these lesions may represent incipient tubular cancers. Nevertheless, such lesions may be satisfactorily treated by simple excision. Since we are certain only about its topographic and clinical behavior, but not its precise biologic nature, we regard the designation nonencapsulated sclerosing lesion most appropriate. Stromal and periductal elastosis was not infrequently encountered in examples of overt sclerosing and blunt ductal adenosis which may mimic, but can readily be distinguished from, the nonencapsulated sclerosing lesion.
对15例乳腺独特的增生性管状病变（费诺利奥和拉特斯病变）进行了组织学研究。尽管该病变始终缺乏脂肪组织浸润，但其一些形态学特征与管状癌的特征有共性，这引发了这些病变可能代表早期管状癌的可能性。然而，此类病变通过简单切除即可得到满意治疗。由于我们仅确定其局部解剖学和临床行为，而不确定其确切生物学性质，因此我们认为非包膜性硬化性病变这一名称最为合适。在明显的硬化性病变和钝性导管腺病的病例中，常可见间质和导管周围弹性组织变性，它们可能会与非包膜性硬化性病变相似，但很容易与之区分。
