Puzyeyeva Olena, Lam Wai Ching, Flanagan John G, Brent Michael H, Devenyi Robert G, Mandelcorn Mark S, Wong Tien, Hudson Christopher
Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, Canada.
J Ophthalmol. 2011;2011:764183. doi: 10.1155/2011/764183. Epub 2011 Sep 29.
Purpose. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality. Methods. The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). Patients were imaged using the Heidelberg Spectralis (Heidelberg Engineering, Germany) in SD-OCT mode. Patients also underwent digital fundus photography and clinical assessment. Results. SD-OCT imaging of a case of age-related macular degeneration revealed a subfoveal choroidal neovascular membrane with detachment of the retinal pigment epithelium (RPE) and neurosensory retina. Using SD-OCT, the cases of DR and BRVO both exhibited macular edema with cystoid spaces visible in the outer retina. Conclusions. The ability of SD-OCT to clearly and objectively elucidate subtle morphological changes within the retinal layers provides information that can be used to formulate diagnoses with greater confidence.
目的。展示一系列通过光谱域光学相干断层扫描（SD - OCT）成像的视网膜疾病病例，以说明这种新成像方式的潜力和局限性。方法。该系列包括年龄相关性黄斑变性（ARMD）、糖尿病性视网膜病变（DR）、视网膜中央动脉阻塞（CRAO）和视网膜分支静脉阻塞（BRVO）各一例的四个选定病例。患者使用德国海德堡工程公司的海德堡Spectralis进行SD - OCT模式成像。患者还接受了数字眼底摄影和临床评估。结果。年龄相关性黄斑变性一例的SD - OCT成像显示黄斑下脉络膜新生血管膜伴视网膜色素上皮（RPE）和神经感觉视网膜脱离。使用SD - OCT，DR和BRVO病例均表现为黄斑水肿，在外层视网膜可见囊样间隙。结论。SD - OCT清晰、客观地阐明视网膜各层细微形态变化的能力提供了可用于更有信心地做出诊断的信息。
