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不同人体测量学指标与冠状动脉粥样硬化负荷的相关性研究。

Association of different anthropometric measures and indices with coronary atherosclerotic burden.

机构信息

Instituto de Geriatria e Gerontologia, PUCRS, Porto Alegre, RS, Brazil.

出版信息

Arq Bras Cardiol. 2011 Nov;97(5):397-401. doi: 10.1590/s0066-782x2011005000093. Epub 2011 Sep 30.

DOI:10.1590/s0066-782x2011005000093
PMID:21971634
Abstract

BACKGROUND

The association between anthropometric parameters and atherosclerotic burden is not well established and few studies have addressed this issue.

OBJECTIVE

To evaluate the association of different anthropometric parameters with the coronary atherosclerotic burden.

METHODS

Adult patients undergoing coronary angiography were enrolled in the study. Sociodemographic characteristics and cardiovascular risk factors were collected through a standardized questionnaire. Weight, height, waist circumference (WC), abdominal circumference (AbC), hip circumference (HC) and neck circumference (NC) were measured and body mass index (BMI), waist-hip ratio (WHR), abdominal circumference-hip ratio (AbCHR) and waist-height ratio (WHtR) were calculated. The atherosclerotic burden at the coronary angiography was measured through Friesinger score (FS). Significant atherosclerosis was considered when FS ≥ 5.

RESULTS

The sample consisted of 337 patients, of whom 213 were men (63.2%). The mean age was 60.1 ± 10 years. Only WHR (r = 0.159 and p = 0.003) showed a significant linear correlation with the coronary atherosclerotic burden as measured by FS. When the sample was stratified by gender, we found a significant correlation between women's AbCHR (r = 0.238 and p = 0.008) and WHR (r = 0.198 and p = 0.028) with FS. Men showed no correlation between anthropometric parameters and FS. After adjusting for gender, age, hypertension, smoking and DM, no anthropometric parameter was associated with coronary atherosclerotic burden as measured by FS in the total sample or when separated by gender.

CONCLUSION

No anthropometric parameter was an independent risk factor for coronary atherosclerotic burden.

摘要

背景

人体测量参数与动脉粥样硬化负担之间的关系尚未得到充分证实,很少有研究涉及到这个问题。

目的

评估不同人体测量参数与冠状动脉粥样硬化负担之间的关系。

方法

本研究纳入了接受冠状动脉造影的成年患者。通过标准化问卷收集了社会人口统计学特征和心血管危险因素。测量体重、身高、腰围(WC)、腹围(AbC)、臀围(HC)和颈围(NC),并计算体重指数(BMI)、腰臀比(WHR)、腹围-臀围比(AbCHR)和腰高比(WHtR)。通过 Friesinger 评分(FS)测量冠状动脉造影的动脉粥样硬化负担。当 FS≥5 时,认为存在显著动脉粥样硬化。

结果

样本包括 337 例患者,其中 213 例为男性(63.2%)。平均年龄为 60.1±10 岁。只有 WHR(r=0.159,p=0.003)与 FS 所示的冠状动脉粥样硬化负担呈显著线性相关。当按性别对样本进行分层时,我们发现女性的 AbCHR(r=0.238,p=0.008)和 WHR(r=0.198,p=0.028)与 FS 之间存在显著相关性。男性的人体测量参数与 FS 之间无相关性。在校正性别、年龄、高血压、吸烟和糖尿病后,在总样本或按性别分层时,没有人体测量参数与 FS 所示的冠状动脉粥样硬化负担相关。

结论

没有人体测量参数是冠状动脉粥样硬化负担的独立危险因素。

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