Institute of Applied Medicines & Research, Ghaziabad, Uttar Pradesh, India.
J Tradit Chin Med. 2011 Sep;31(3):246-50.
To investigate antimicrobial potential of aqueous (infusions, decoctions) and methanlic extracts (1:2 and 1:5 concentrations) of Emblica officinalis (amla) against seven pathogenic bacteria namely Staphylococcs aureus, Staphylococcus saprophyticus, Escherichia coli, Enterococcus faecalis, Enterococcus cloacae, Proteus vulgaris and Klebsiella pneumoniae.
The well diffusion technique was employed. The minimum inhibitory concentration (MIC) was determined using micro-broth dilution methods and phytochemical screening was done as per standard procedures.
Aqueous infusion extract of amla exhibited potent antimicrobial activity against E. cloacae followed by E. coli. Preliminary phytochemical analysis of E. officinalis aqueous extracts (infusions and decoctions) only showed presence of tannins, saponins, flavanoids, Terpenoids and phenols. MIC of aqueous extract of E. officinalis was most active against K. pneumoniae. Whereas MIC of methanol extract of E. officinalis shows maximum activity against E. coli.
Emblica officinalis definitely possesses potent antimicrobial activities and this can serve as an important platform for the development of inexpensive, safe and effective medicines
研究印度醋栗（amla）的水（浸剂、煎剂）和甲醇（浓度 1:2 和 1:5）提取物对七种致病菌（金黄色葡萄球菌、腐生性葡萄球菌、大肠杆菌、粪肠球菌、阴沟肠球菌、普通变形杆菌和肺炎克雷伯菌）的抗菌潜力。
采用平板扩散法。采用微量肉汤稀释法测定最小抑菌浓度（MIC），并按标准程序进行植物化学筛选。
醋栗水浸剂提取物对阴沟肠球菌和大肠杆菌表现出较强的抗菌活性。印度醋栗水提取物（浸剂和煎剂）的初步植物化学分析仅显示存在单宁、皂苷、类黄酮、萜类化合物和酚类。印度醋栗水提取物的 MIC 对肺炎克雷伯菌最有效。而印度醋栗甲醇提取物的 MIC 对大肠杆菌表现出最大的活性。
印度醋栗确实具有很强的抗菌活性，这可以为开发廉价、安全、有效的药物提供重要平台。
