职业性哮喘的发病机制和疾病机制。
Pathogenesis and disease mechanisms of occupational asthma.
机构信息
Department of Internal Medicine, University of Cincinnati College of Medicine, 3255 Eden Avenue, Cincinnati, OH 45267-0563, USA.
出版信息
Immunol Allergy Clin North Am. 2011 Nov;31(4):699-716, vi. doi: 10.1016/j.iac.2011.07.008.
Abstract
Occupational asthma (OA) is one of the most common forms of work-related lung disease in all industrialized nations. The clinical management of patients with OA depends on an understanding of the multifactorial pathogenetic mechanisms that can contribute to this disease. This article discusses the various immunologic and nonimmunologic mechanisms and genetic susceptibility factors that drive the inflammatory processes of OA.
摘要
职业性哮喘（OA）是所有工业化国家中最常见的职业性肺部疾病之一。OA 患者的临床管理取决于对可能导致这种疾病的多因素发病机制的理解。本文讨论了驱动 OA 炎症过程的各种免疫和非免疫机制以及遗传易感性因素。
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