Bush T L
Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205.
Ann N Y Acad Sci. 1990;592:263-71; discussion 334-45. doi: 10.1111/j.1749-6632.1990.tb30338.x.
This manuscript has described the principal modifiable risk factors for the major killer of postmenopausal women. Clearly women who smoke should be convinced to quit, and those who have hypertension and hypercholesterolemia should be encouraged initially to adopt hygienic interventions (that is weight reduction and moderate exercise) to lower their blood pressures and cholesterol levels. Further, given the magnitude of the risk reduction in CVD seen in estrogen users, estrogen use ought to be considered as a preventive therapy for postmenopausal women, but particularly for those who are at high risk of cardiovascular disease.
本手稿描述了绝经后女性主要杀手的主要可改变风险因素。显然,应该说服吸烟的女性戒烟,对于患有高血压和高胆固醇血症的女性,应首先鼓励她们采取卫生干预措施(即减重和适度运动)来降低血压和胆固醇水平。此外,鉴于雌激素使用者心血管疾病风险降低的幅度,雌激素的使用应被视为绝经后女性的一种预防性治疗方法,尤其是对于那些心血管疾病高危女性。