Department of Health Outcomes and Behavior, Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA.
Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2035-41. doi: 10.1158/1055-9965.EPI-11-0563.
Quality of life assessment has a number of important applications in research on cancer survivors. These applications include use in observational studies to characterize the nature and extent of problems patients experience as well as use in randomized controlled trials to evaluate the relative impact of different cancer treatments or to evaluate the efficacy of interventions designed to improve patient well-being. The aims of this article are to provide an overview of the construct of quality of life and describe strategies commonly used to measure quality of life in adult cancer survivors. In addition, several priorities for future research are identified that involve how quality of life is measured, in whom it is measured, and what uses are made of quality of life data in the clinical care of cancer survivors.
生活质量评估在癌症幸存者研究中有许多重要的应用。这些应用包括在观察性研究中用于描述患者所经历问题的性质和程度,以及在随机对照试验中用于评估不同癌症治疗方法的相对影响,或评估旨在改善患者幸福感的干预措施的效果。本文的目的是提供对生活质量的结构的概述,并描述在成年癌症幸存者中测量生活质量的常用策略。此外,还确定了未来研究的几个优先事项,这些事项涉及如何测量生活质量、在谁身上进行测量以及如何在癌症幸存者的临床护理中使用生活质量数据。