多发性硬化症的主要病因是环境因素：遗传学起次要作用——的确如此。 - Suppr

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The major cause of multiple sclerosis is environmental: genetics has a minor role--yes.

作者信息

Taylor Bruce V

机构信息

Menzies Research Institute, University of Tasmania, Locked Bag 23, Hobart, Tasmania 7001, Australia.

出版信息

Mult Scler. 2011 Oct;17(10):1171-3. doi: 10.1177/1352458511421105.

DOI:10.1177/1352458511421105

PMID:21980150

Abstract

摘要

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The major cause of multiple sclerosis is environmental: genetics has a minor role--yes.

作者信息

Taylor Bruce V

机构信息

Menzies Research Institute, University of Tasmania, Locked Bag 23, Hobart, Tasmania 7001, Australia.

出版信息

Mult Scler. 2011 Oct;17(10):1171-3. doi: 10.1177/1352458511421105.

DOI:10.1177/1352458511421105

PMID:21980150

Abstract

摘要

相似文献

The major cause of multiple sclerosis is environmental: genetics has a minor role--yes.

Mult Scler. 2011 Oct;17(10):1171-3. doi: 10.1177/1352458511421105.

Genetics meets environment: evaluating gene-environment interactions in neurologic diseases.

Semin Neurol. 2011 Nov;31(5):553-61. doi: 10.1055/s-0031-1299793. Epub 2012 Jan 21.

The major cause of multiple sclerosis is environmental: genetics has a minor role--no.

Mult Scler. 2011 Oct;17(10):1174-5. doi: 10.1177/1352458511421106.

The major cause of multiple sclerosis is environmental: genetics has a minor role--commentary.

Mult Scler. 2011 Oct;17(10):1176. doi: 10.1177/1352458511421107.

[Environment, genetics and immunology in multiple sclerosis].

Rev Prat. 1999 Nov 1;49(17):1853-60.

The multiple sclerosis trait and the development of multiple sclerosis: genetic vulnerability and environmental effect.

Clin Neurol Neurosurg. 2006 Mar;108(3):227-33. doi: 10.1016/j.clineuro.2005.11.019. Epub 2006 Jan 6.

An overview of gene-epigenetic-environmental contributions to MS causation.

J Neurol Sci. 2009 Nov 15;286(1-2):54-7. doi: 10.1016/j.jns.2009.06.037. Epub 2009 Jul 19.

[Genetic and environmental factors in multiple sclerosis].

Rev Neurol. 2000;30(10):964-7.

Etiology and pathogenesis of multiple sclerosis.

Semin Neurol. 1998;18(3):287-94. doi: 10.1055/s-2008-1040879.

[Genetic predisposition for multiple sclerosis].

Pathol Biol (Paris). 2000 Feb;48(1):87-92.

引用本文的文献

Genes, Gene Loci, and Their Impacts on the Immune System in the Development of Multiple Sclerosis: A Systematic Review.

Int J Mol Sci. 2024 Nov 30;25(23):12906. doi: 10.3390/ijms252312906.

Lactobacillaceae differentially impact butyrate-producing gut microbiota to drive CNS autoimmunity.

Gut Microbes. 2024 Jan-Dec;16(1):2418415. doi: 10.1080/19490976.2024.2418415. Epub 2024 Oct 27.

Developing a clinical-environmental-genotypic prognostic index for relapsing-onset multiple sclerosis and clinically isolated syndrome.

Brain Commun. 2021 Dec 4;3(4):fcab288. doi: 10.1093/braincomms/fcab288. eCollection 2021.

Immunoregulatory Effects of Tolerogenic Probiotics in Multiple Sclerosis.

Adv Exp Med Biol. 2021;1286:87-105. doi: 10.1007/978-3-030-55035-6_6.

Relationship between miR-155 and miR-146a polymorphisms and susceptibility to multiple sclerosis in an Egyptian cohort.

Biomed Rep. 2020 May;12(5):276-284. doi: 10.3892/br.2020.1286. Epub 2020 Mar 4.

Western lifestyle and immunopathology of multiple sclerosis.

Ann N Y Acad Sci. 2018 Apr;1417(1):71-86. doi: 10.1111/nyas.13583. Epub 2018 Jan 27.

Novel Therapeutics for Multiple Sclerosis Designed by Parasitic Worms.

Int J Mol Sci. 2017 Oct 13;18(10):2141. doi: 10.3390/ijms18102141.

Correlation between CTLA-4 gene rs221775A>G single nucleotide polymorphism and multiple sclerosis susceptibility. A meta-analysis.

Open Med (Wars). 2016 Jul 22;11(1):264-269. doi: 10.1515/med-2016-0052. eCollection 2016.

Assessing the Risk Factors for Multiple Sclerosis in Women of Reproductive Age Suffering the Disease in Isfahan Province.

Int J Prev Med. 2016 Mar 10;7:58. doi: 10.4103/2008-7802.178532. eCollection 2016.

Noise in multiple sclerosis: unwanted and necessary.

Ann Clin Transl Neurol. 2014 Jul;1(7):502-11. doi: 10.1002/acn3.72. Epub 2014 Jun 19.