Department of Epidemiology, School of Public Health, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China.
Parasit Vectors. 2011 Oct 7;4:194. doi: 10.1186/1756-3305-4-194.
Worldwide schistosomiasis continues to be a serious public health problem. Over the past five decades, China has made remarkable progress in reducing Schistosoma japonicum infections in humans to a relatively low level. Endemic regions are currently circumscribed in certain core areas where re-infection and repeated chemotherapy are frequent. At present, selective chemotherapy with praziquantel is one of the main strategies in China's National Schistosomiasis Control Program, and thus diagnosis of infected individuals is a key step for such control. In this paper we review the current status of our knowledge about diagnostic tools for schistosomiasis japonica. A simple, affordable, sensitive, and specific assay for field diagnosis of schistosomiasis japonica is not yet available, and this poses great barriers towards full control of schistosomiasis. Hence, a search for a diagnostic approach, which delivers these characteristics, is essential and should be given high priority.
全球血吸虫病仍然是一个严重的公共卫生问题。在过去的五十年中，中国在降低人体日本血吸虫感染方面取得了显著进展，感染水平已降至相对较低。目前，疫区局限于某些核心地区，这些地区经常出现再感染和反复化疗的情况。目前，用吡喹酮进行选择性化疗是中国国家血吸虫病控制规划的主要策略之一，因此，诊断感染个体是控制的关键步骤。本文综述了我们目前对日本血吸虫病诊断工具的认识。目前还没有一种简单、经济、敏感、特异的现场诊断日本血吸虫病的方法，这给血吸虫病的全面控制带来了很大的障碍。因此，寻找一种具有这些特性的诊断方法至关重要，应给予高度优先考虑。
