Marquardt Katrin, Büttner Heinz H, Broschewitz Ulf, Barten Malte, Schneider Volker
Pathology Laboratory, Schwerin, Germany.
Acta Cytol. 2011;55(5):433-7. doi: 10.1159/000331811. Epub 2011 Oct 8.
It was the aim of this study to determine the screening history of all invasive cervical carcinomas between 2004 and 2009 in one of the Federal States of Germany.
The pooled data sets of all in-state laboratories, corrected and supplemented by data of the State Cancer Registry, were used. The screening histories of all patients, their age and tumor types were collated and analyzed.
Of 617 patients with invasive carcinoma of the cervix, 373 (60%) had not had a cervical smear within the past 5 years. In 188 patients (31%), an incomplete screening history was found, whereas only 9% of women had participated regularly. In non-participants, late tumor stages (stage T1B and higher) were predominant and found in 86%. In contrast, in the group with regular screening histories more than half of all cases (54%) were microinvasive carcinomas (stage T1A) with excellent prognosis. Lack of follow-up or refusal of treatment by patients played a minor yet significant role.
Non-participation is still by far the most common reason for persistent cases of cervical carcinoma in the German screening program.
本研究旨在确定德国某联邦州2004年至2009年间所有浸润性宫颈癌的筛查史。
使用了该州所有实验室的汇总数据集，并由州癌症登记处的数据进行校正和补充。整理并分析了所有患者的筛查史、年龄和肿瘤类型。
在617例浸润性宫颈癌患者中，373例（60%）在过去5年内未进行过宫颈涂片检查。188例患者（31%）的筛查史不完整，而只有9%的女性定期参与筛查。在未参与者中，晚期肿瘤阶段（T1B期及更高）占主导，占86%。相比之下，在筛查史规律的组中，超过一半的病例（54%）为微浸润癌（T1A期），预后良好。患者缺乏随访或拒绝治疗起到了较小但显著的作用。
在德国的筛查项目中，不参与筛查仍然是宫颈癌持续存在病例的最常见原因。
