European Palliative Reasearch Center, Department of Cancer Research and Molecular Medicine, NTNU, Faculty of Medicine, Trondheim, Norway.
Curr Opin Support Palliat Care. 2011 Dec;5(4):350-5. doi: 10.1097/SPC.0b013e32834c4a05.
Cachexia is a common negative consequence of cancer and is often unrecognized. To assess cachexia, malnutrition assessment tools are used. This review discusses the advantages and disadvantages of the current malnutrition assessment tools and describes the requirements for a comprehensive cachexia assessment instrument and its implication for clinics and research.
The historic definition of cachexia has been updated based on new understanding of mechanism and clinical concepts. Classification of cachectic patients includes novel domains and stages. Validated cachexia assessment tools based on the new classification are under development.
Cachexia has an impact for patients and proxies. Due to a lack of formal cachexia assessment instrument, malnutrition assessment tools are in use. Future comprehensive cachexia assessment instruments will identify cachexia domains and stages and classify cachexia, the basis for better clinical treatment and research.
恶病质是癌症的常见负面后果,且常被忽视。为评估恶病质,使用营养不良评估工具。本文讨论了当前营养不良评估工具的优缺点,并描述了全面恶病质评估工具的要求及其对临床和研究的意义。
基于对机制和临床概念的新认识,恶病质的历史定义已得到更新。恶病质患者的分类包括新的领域和阶段。正在开发基于新分类的经验证的恶病质评估工具。
恶病质对患者及其代理人有影响。由于缺乏正式的恶病质评估工具,因此使用营养不良评估工具。未来全面的恶病质评估工具将确定恶病质领域和阶段,并对恶病质进行分类,这是更好的临床治疗和研究的基础。