Schofield N M, White J B
Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford.
BMJ. 1989 Dec 2;299(6712):1371-5. doi: 10.1136/bmj.299.6712.1371.
To investigate the incidence of difficulties associated with parental presence during the induction of anaesthesia in children and the influence of premedication with special reference to vomiting after papaveretum.
Mixed factual and multiple choice questionnaire completed by medical and nursing staff and parents during and after admission.
Teaching hospital with regional paediatric general surgical unit where parental presence during induction of anaesthesia is long established.
151 Children aged 1-14 years who had not previously undergone surgery attending with parents for day stay general surgical procedures.
Children were randomly allocated to receive no premedication (group 1), oral diazepam elixir (0.3 mg/kg) (group 2), or intramuscular papaveretum with hyoscine (0.3 mg/kg with 0.006 mg/kg) (group 3). No other modification to established day stay routine was made.
No major problems were associated with the presence of parents during the induction of anaesthesia. Only 10 of the 141 parents who accompanied their child caused some difficulty, and five became distressed. Premedication with both diazepam and papaveretum resulted in sedation but did not ease induction of anaesthesia. Papaveretum greatly reduced pain and distress immediately after the operation, pain and discomfort being observed in only 15% of children (7/48) compared with 66% (27/41) in group 1 and 49% (22/45) in group 2. Papaveretum, however, must be given intramuscularly, and nurses observed that the children preferred being given premedication orally to intramuscularly. In addition, the incidences of nausea and vomiting were significantly higher in the postoperative ward and at home with papaveretum, although no patient who had been given the drug was nauseous or vomited in the recovery area. The incidences of nausea in group 3 were 62% (31/50) and 57% (27/47) in the postoperative ward and at home, respectively, v 21% (7/33) and 14% (4/29) in group 1 and 13% (5/38) and 14% (5/37) in group 2; the incidences of vomiting in group 3 were 60% and 43% in the postoperative ward and at home, respectively, v 18% and 7% in group 1 and 11% and 11% in group 2. Finally, neither the administration or otherwise of premedication nor the drug given affected the children's or parents' perception of day care surgery.
Difficulties with parents in anaesthetic rooms were not common or severe. Premedication provides preoperative sedation and papaveretum improves the immediate postoperative course but the incidences of nausea and vomiting after operation are higher with its use than without.
调查儿童麻醉诱导期间家长在场相关困难的发生率,以及术前用药的影响,特别提及吗啡后呕吐情况。
医护人员及家长在患儿入院期间及出院后完成的事实与多项选择题混合问卷。
设有区域儿科普通外科病房的教学医院,麻醉诱导期间家长在场的做法由来已久。
151名1 - 14岁此前未接受过手术的儿童,由家长陪同前来接受日间普通外科手术。
将儿童随机分为三组,分别为不进行术前用药(第1组)、口服地西泮酏剂(0.3毫克/千克)(第2组)、肌内注射吗啡加东莨菪碱(0.3毫克/千克加0.006毫克/千克)(第3组)。既定的日间手术常规未作其他改动。
麻醉诱导期间家长在场未引发重大问题。141名陪同孩子的家长中只有10人造成了一些困难,5人感到苦恼。地西泮和吗啡术前用药均导致镇静,但未减轻麻醉诱导难度。吗啡极大地减轻了术后即刻的疼痛和苦恼,仅15%(7/48)的儿童出现疼痛和不适,而第1组为66%(27/41),第2组为49%(22/45)。然而,吗啡必须肌内注射,护士观察到儿童更喜欢口服而非肌内注射术前用药。此外,使用吗啡后,术后病房及家中恶心和呕吐的发生率显著更高,尽管用药患儿在恢复区均未出现恶心或呕吐。第3组术后病房及家中恶心发生率分别为62%(31/50)和57%(27/47),而第1组分别为21%(7/33)和14%(4/29),第2组分别为13%(5/38)和14%(5/37);第3组术后病房及家中呕吐发生率分别为60%和43%,而第1组分别为18%和7%,第2组分别为11%和11%。最后,术前用药与否及所用药剂均未影响儿童或家长对日间手术的看法。
麻醉室中家长带来的困难并不常见或严重。术前用药可提供术前镇静,吗啡可改善术后即刻情况,但使用后术后恶心和呕吐的发生率高于未使用者。