Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.
Viruses. 2011 Apr;3(4):336-46. doi: 10.3390/v3040336. Epub 2011 Apr 12.
Actin is important for a variety of cellular processes, including uptake of extracellular material and intracellular transport. Several emerging lines of evidence indicate that herpesviruses exploit actin and actin-associated myosin motors for viral entry, intranuclear transport of capsids, and virion egress. The goal of this review is to explore these processes and to highlight potential future directions for this area of research.
肌动蛋白对于多种细胞过程很重要,包括细胞外物质的摄取和细胞内运输。一些新出现的证据表明,疱疹病毒利用肌动蛋白和肌球蛋白马达来进行病毒进入、衣壳的核内运输和病毒粒子的出芽。本文的目的是探讨这些过程,并强调该研究领域的潜在未来方向。