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柯达Surecell衣原体检测试剂盒与培养法在诊断婴儿衣原体性结膜炎中的比较。

Comparison of Kodak Surecell Chlamydia Test Kit with culture for the diagnosis of chlamydial conjunctivitis in infants.

作者信息

Hammerschlag M R, Gelling M, Roblin P M, Worku M

机构信息

Department of Pediatrics, State University of New York Health Science Center, Brooklyn 11203.

出版信息

J Clin Microbiol. 1990 Jun;28(6):1441-2. doi: 10.1128/jcm.28.6.1441-1442.1990.

DOI:10.1128/jcm.28.6.1441-1442.1990
PMID:2199506
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267949/
Abstract

The accuracy of the Surecell Chlamydia Test Kit (Kodak Clinical Products, Rochester, N.Y.) in detecting neonatal conjunctival infection caused by Chlamydia trachomatis was determined by comparison of this enzyme immunoassay with the isolation of C. trachomatis in tissue culture. Kodak Surecell is a rapid monoclonal antibody-based membrane capture enzyme immunoassay which can be processed in the office of a physician. The sensitivity and specificity compared to culture in detecting C. trachomatis in conjunctival specimens from infants with conjunctivitis were 93 and 96%, respectively. The test does not require specialized equipment or trained personnel and would be ideal for physicians who see low numbers of infants with possible chlamydial conjunctivitis in their offices.

摘要

通过将Surecell衣原体检测试剂盒(柯达临床产品公司,纽约州罗切斯特)与沙眼衣原体在组织培养中的分离情况进行比较,确定了该试剂盒检测新生儿沙眼衣原体所致结膜感染的准确性。柯达Surecell是一种基于单克隆抗体的快速膜捕获酶免疫测定法,可在医生办公室进行检测。在检测结膜炎婴儿结膜标本中的沙眼衣原体时,与培养法相比,其敏感性和特异性分别为93%和96%。该检测不需要专门设备或经过培训的人员,对于在办公室中诊治少量可能患有衣原体性结膜炎婴儿的医生来说是理想之选。

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本文引用的文献

1
Rapid diagnosis of Chlamydia trachomatis pneumonia in infants by direct immunofluorescence microscopy of nasopharyngeal secretions.通过鼻咽分泌物直接免疫荧光显微镜检查快速诊断婴儿沙眼衣原体肺炎
J Pediatr. 1986 Oct;109(4):653-5. doi: 10.1016/s0022-3476(86)80232-3.
2
Comparison of enzyme immunoassay and culture for diagnosis of chlamydial conjunctivitis and respiratory infections in infants.酶免疫测定法与培养法在诊断婴儿衣原体性结膜炎和呼吸道感染中的比较
J Clin Microbiol. 1987 Dec;25(12):2306-8. doi: 10.1128/jcm.25.12.2306-2308.1987.
3
Comparison of two rapid microscopic methods and culture for detection of Chlamydia trachomatis in ocular and nasopharyngeal specimens from infants.两种快速显微镜检查方法与培养法在检测婴儿眼和鼻咽标本中沙眼衣原体的比较
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4
TestPack Chlamydia, a new rapid assay for the direct detection of Chlamydia trachomatis.衣原体检测试剂盒,一种用于直接检测沙眼衣原体的新型快速检测方法。
J Clin Microbiol. 1989 Dec;27(12):2811-4. doi: 10.1128/jcm.27.12.2811-2814.1989.
5
Assessment of neonatal conjunctivitis with a direct immunofluorescent monoclonal antibody stain for Chlamydia.采用针对衣原体的直接免疫荧光单克隆抗体染色法评估新生儿结膜炎。
JAMA. 1986 Jun 27;255(24):3369-73.