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分娩诱导后母婴结局:一项队列研究。

Maternal and neonatal outcomes following induction of labor: a cohort study.

机构信息

Discipline of Obstetrics and Gynaecology, University of Adelaide, South Australia, Australia.

出版信息

Acta Obstet Gynecol Scand. 2012 Feb;91(2):198-203. doi: 10.1111/j.1600-0412.2011.01298.x. Epub 2011 Nov 15.

DOI:10.1111/j.1600-0412.2011.01298.x
PMID:21995778
Abstract

OBJECTIVE

To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor.

DESIGN

Cohort study.

SETTING

A state-wide perinatal outcome database.

POPULATION

28,626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications.

METHODS

Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model.

MAIN OUTCOME MEASURES

Cesarean section, assisted vaginal birth, important measures of maternal and neonatal morbidity.

RESULTS

Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95% CI 1.55-1.80). The lowest risk of adverse maternal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor.

CONCLUSIONS

Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.

摘要

目的

评估按孕周和临产开始评估的足月分娩的母婴结局。

设计

队列研究。

地点

全州围产期结局数据库。

人群

28626 名自发性临产、因明确指征行引产和因非明确指征行引产的妇女。

方法

利用经过验证的数据集进行队列研究,使用对数二项式模型比较不同临产开始类型的结局。

主要观察指标

剖宫产术、辅助阴道分娩、母婴发病率的重要指标。

结果

因非明确指征行引产与一系列结局的风险显著增加相关,包括剖宫产术(RR 1.67,95%CI 1.55-1.80)。在 38 周至 39 周之间分娩和自发性临产时,母婴不良结局的风险最低。

结论

足月时因非明确指征行引产与不良结局风险增加相关。在无其他并发症的情况下,应谨慎对待足月时引产的宽松政策。

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