Department of Chemistry, Rhodes University, Grahamstown, South Africa.
Anal Chim Acta. 2011 Nov 7;706(1):25-36. doi: 10.1016/j.aca.2011.08.021. Epub 2011 Aug 19.
Challenges associated with analyte and matrix complexities and the ever increasing pressure from all sectors of industry for alternative analytical devices, have necessitated the development and application of new materials in analytical chemistry. To date, nanomaterials have emerged as having excellent properties for analytical chemistry applications mainly due to their large surface area to volume ratio and the availability of a wide variety of chemical and morphological modification methods. Of the available nanofibrous material fabrication methods, electrospinning has emerged as the most versatile. It is the aim of this contribution to highlight some of the recent developments that harness the great potential shown by electrospun nanofibers for application in analytical chemistry. The review discusses the use of electrospun nanofibers as a platform for low resolution separation or as a chromatographic sorbent bed for high resolution separation. It concludes by discussing the applications of electrospun nanofibers in detection systems with a specific focus on the development of simple electrospun nanofiber based colorimetric probes.
分析物和基质复杂性带来的挑战，以及工业各领域对替代分析设备的压力不断增加，都需要在分析化学中开发和应用新材料。迄今为止，纳米材料因其具有出色的分析化学应用性能而崭露头角，主要是因为它们具有大的表面积与体积比，并且有多种化学和形态修饰方法。在现有的纳米纤维材料制造方法中，静电纺丝已经脱颖而出，成为最通用的方法。本文旨在强调利用静电纺纳米纤维在分析化学中的巨大潜力的一些最新进展。综述讨论了将静电纺纳米纤维用作低分辨率分离的平台，或用作高效分离的色谱固定相。最后，讨论了静电纺纳米纤维在检测系统中的应用，特别关注基于简单静电纺纳米纤维的比色探针的发展。
