Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, China.
Adv Mater. 2011 Dec 1;23(45):5392-7. doi: 10.1002/adma.201103521. Epub 2011 Oct 14.
A simple seed-mediated growth route is developed to fabricate monodisperse, uniform superparamagnetic Fe(3)O(4) core/gold shell structured nanocomposites with tunable sizes and optical properties, in which gold seed formation and attachment onto the core surface via S-Au covalent bonding proceeds almost simultaneously in the one-pot synthesis. The as-prepared nanocomposite is demonstrated to have a great potential for magnetic resonance imaging (MRI)-guided, focused photothermal tumor therapy under near-IR laser radiation.
一种简单的种子介导生长方法被开发出来，用于制备具有可调尺寸和光学性质的单分散、均匀的超顺磁 Fe(3)O(4)核/金壳结构的纳米复合材料，其中金种子的形成和通过 S-Au 共价键附着到核表面几乎同时进行在一锅合成中进行。所制备的纳米复合材料在近红外激光辐射下具有磁共振成像（MRI）引导、聚焦光热肿瘤治疗的巨大潜力。
