Shi Xiaolu, Tian Ye, Liu Yang, Xiong Zhengrong, Zhai Shaobo, Chu Shunli, Gao Fengxiang
Department of Implantology, Hospital of Stomatology, Jilin University, Changchun, China.
University of Science and Technology of China, Hefei, China.
Front Oncol. 2022 Jul 6;12:939365. doi: 10.3389/fonc.2022.939365. eCollection 2022.
The aggressive growth of cancer cells brings extreme challenges to cancer therapy while triggering the exploration of the application of multimodal therapy methods. Multimodal tumor therapy based on photothermal nanomaterials is a new technology to realize tumor cell thermal ablation through near-infrared light irradiation with a specific wavelength, which has the advantages of high efficiency, less adverse reactions, and effective inhibition of tumor metastasis compared with traditional treatment methods such as surgical resection, chemotherapy, and radiotherapy. Photothermal nanomaterials have gained increasing interest due to their potential applications, remarkable properties, and advantages for tumor therapy. In this review, recent advances and the common applications of photothermal nanomaterials in multimodal tumor therapy are summarized, with a focus on the different types of photothermal nanomaterials and their application in multimodal tumor therapy. Moreover, the challenges and future applications have also been speculated.
癌细胞的侵袭性生长给癌症治疗带来了极大挑战，同时也引发了对多模态治疗方法应用的探索。基于光热纳米材料的多模态肿瘤治疗是一种通过特定波长的近红外光照射实现肿瘤细胞热消融的新技术，与手术切除、化疗和放疗等传统治疗方法相比，具有高效、不良反应少以及有效抑制肿瘤转移等优点。光热纳米材料因其潜在应用、卓越性能以及在肿瘤治疗方面的优势而受到越来越多的关注。在本综述中，总结了光热纳米材料在多模态肿瘤治疗中的最新进展和常见应用，重点介绍了不同类型的光热纳米材料及其在多模态肿瘤治疗中的应用。此外，还对面临的挑战和未来应用进行了推测。
