Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Laryngoscope. 2011 Dec;121(12):2521-5. doi: 10.1002/lary.22365. Epub 2011 Oct 13.
OBJECTIVES/HYPOTHESIS: To investigate patient outcomes with large-diameter bougienage in isolated cricopharyngeal dysfunction and understand how esophageal dilatation can be used as an effective diagnostic and therapeutic modality in treating dysphagia.
Retrospective review.
A retrospective chart review was performed on 46 patients meeting the criteria for cricopharyngeal dysphagia from 2004 to 2008 presenting in the outpatient setting. Patients were treated with 60 French esophageal dilators. Outcomes were analyzed as a function of symptomatology, manometry, duration of benefit, and safety.
Over the period reviewed, 59 dilatations were performed on 46 patients with cricopharyngeal dysfunction. Eight patients were dilated more than once. Four patients were lost to follow-up. The average starting Functional Outcome Swallowing Score (FOSS) was 2.07. Of the patients reviewed, 64.29% experienced an improvement in their FOSS with a median duration of 741 days. There were five minor complications and no major complications.
In the largest series of esophageal dilatation for cricopharyngeal dysfunction in the literature, we found large-bore bougienage to have significant utility due to its efficacy, ease of use, and safety when compared to other modalities such as botulinum injection, balloon dilatation, and cricopharyngeal myotomy.
目的/假设:研究大直径探条扩张术治疗孤立性环咽肌功能障碍患者的结局,并了解食管扩张术如何作为一种有效诊断和治疗吞咽困难的方法。
回顾性研究。
对 2004 年至 2008 年在门诊就诊的符合环咽肌吞咽困难标准的 46 例患者进行回顾性图表审查。患者采用 60Fr 食管扩张器进行治疗。分析了症状、测压、获益持续时间和安全性的结果。
在审查期间,对 46 例环咽肌功能障碍患者进行了 59 次扩张,其中 8 例患者进行了多次扩张,4 例患者失访。平均起始功能吞咽评分(FOSS)为 2.07。在接受评估的患者中,64.29%的患者 FOSS 得到改善,中位数获益持续时间为 741 天。有 5 例轻微并发症,无严重并发症。
在文献中对环咽肌功能障碍进行的最大规模食管扩张系列研究中,与肉毒杆菌注射、球囊扩张和环咽肌切开术等其他方法相比,大口径探条扩张术因其疗效、易用性和安全性而具有显著的实用性。