检测万古霉素耐药粪肠球菌医院分离株中一种不常见的 van 基因型。
Detection of an unusual van genotype in a vancomycin-resistant Enterococcus faecium hospital isolate.
机构信息
Department of Laboratory Medicine, National University Hospital, Singapore 119074, Republic of Singapore.
出版信息
J Clin Microbiol. 2011 Dec;49(12):4297-8. doi: 10.1128/JCM.05524-11. Epub 2011 Oct 12.
Abstract
We highlight the detection of a rare vanM genotype in Enterococcus faecium. This isolate exhibited a VanB phenotype, with high levels of resistance to vancomycin (MIC, >256 mg/liter) and susceptibility to teicoplanin (MIC, 1 mg/liter). It was, however, vanB negative by PCR. Further screening for other van loci revealed the presence of a complete vanM operon.
摘要
我们强调了肠球菌中罕见的 vanM 基因型的检测。该分离株表现出 VanB 表型，对万古霉素（MIC，>256 毫克/升）高度耐药，但对替考拉宁（MIC，1 毫克/升）敏感。然而，PCR 检测结果为 vanB 阴性。进一步筛选其他的 van 基因座显示存在完整的 vanM 操纵子。
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