定期健康检查,1999年更新:1. 肥胖的检测、预防与治疗。加拿大预防保健特别工作组。
Periodic health examination, 1999 update: 1. Detection, prevention and treatment of obesity. Canadian Task Force on Preventive Health Care.
作者信息
Douketis J D, Feightner J W, Attia J, Feldman W F
出版信息
CMAJ. 1999 Feb 23;160(4):513-25.
OBJECTIVES
(1) To evaluate the evidence relating to the effectiveness of methods to prevent and treat obesity, and (2) to provide recommendations for the prevention and treatment of obesity in adults aged 18 to 65 years and for the measurement of the body mass index (BMI) as part of a periodic health examination.
OPTIONS
In adults with obesity (BMI greater than 27) management options include weight reduction, prevention of further weight gain or no intervention.
OUTCOMES
The long-term (more than 2 years) effectiveness of (a) methods to prevent obesity and (b) methods to treat obesity.
EVIDENCE
MEDLINE was searched for articles published from 1966 to April 1998 that related to the prevention and treatment of obesity; additional articles were identified from the bibliographies of review articles and the listings of Current Contents. Selection criteria were used to limit the analysis to prospective studies with at least 2 years' follow-up.
BENEFITS, HARM AND COSTS: Health benefits of weight reduction were evaluated in terms of alleviation of symptoms, improved management of obesity-related diseases and a reduction in major clinical outcomes. The health risk of weight-reduction methods were briefly evaluated in terms of increased mortality and morbidity.
VALUES
The recommendations of this report reflect the commitment of the Canadian Task Force on Preventive Health Care to provide a structured, evidence-based appraisal of whether a manoeuvre should be part of a periodic health examination.
RECOMMENDATIONS
(1) PREVENTION: There is insufficient evidence to recommend in favour of or against community-based obesity prevention programs; however, because of considerable health risks associated with obesity and the limited long-term effectiveness of weight-reduction methods, the prevention of obesity should be a high priority for health care providers (grade C recommendation). (2) TREATMENT: (a) For obese adults without obesity-related diseases, there is insufficient evidence to recommend in favour of or against weight-reduction therapy because of a lack of evidence supporting the long-term effectiveness of weight-reduction methods (grade C recommendation); (b) for obese adults with obesity-related diseases (e.g., diabetes mellitus, hypertension), weight reduction is recommended because it can alleviate symptoms and reduce drug therapy requirements, at least in the short term (grade B recommendation). (3) Detection: (a) for people without obesity-related diseases, there is insufficient evidence to recommend the inclusion or exclusion of BMI measurement as part of a periodic health examination, and therefore BMI measurement is left to the discretion of individual health care providers (grade C recommendation); (b) for people with obesity-related diseases, BMI measurement is recommended because weight reduction should be considered with a BMI of more than 27 (grade B recommendation).
VALIDATION
The findings of this analysis were reviewed through an iterative process by the members of the Canadian Task Force on Preventive Health Care.
SPONSORS
The Canadian Task Force on Preventive Health Care is funded through a partnership between the Provincial and Territorial Ministries of Health and Health Canada.
目标
(1)评估与预防和治疗肥胖方法的有效性相关的证据,以及(2)为18至65岁成年人的肥胖预防和治疗以及将体重指数(BMI)测量作为定期健康检查的一部分提供建议。
选项
在肥胖成人(BMI大于27)中,管理选项包括减轻体重、防止体重进一步增加或不进行干预。
结果
(a)预防肥胖方法和(b)治疗肥胖方法的长期(超过2年)有效性。
证据
检索MEDLINE中1966年至1998年4月发表的与肥胖预防和治疗相关的文章;从综述文章的参考文献和《现刊目次》列表中确定其他文章。使用选择标准将分析限制在至少有2年随访的前瞻性研究。
益处、危害和成本:根据症状缓解、肥胖相关疾病管理的改善以及主要临床结局的减少来评估减轻体重的健康益处。根据死亡率和发病率的增加简要评估减轻体重方法的健康风险。
价值观
本报告的建议反映了加拿大预防保健工作组致力于对一项操作是否应作为定期健康检查的一部分进行结构化、基于证据的评估。
建议
(1)预防:没有足够的证据支持或反对基于社区的肥胖预防计划;然而,由于与肥胖相关的相当大的健康风险以及减轻体重方法的长期有效性有限,肥胖预防应成为医疗保健提供者的高度优先事项(C级建议)。(2)治疗:(a)对于没有肥胖相关疾病的肥胖成年人,由于缺乏支持减轻体重方法长期有效性的证据,没有足够的证据支持或反对减轻体重治疗(C级建议);(b)对于患有肥胖相关疾病(如糖尿病、高血压)的肥胖成年人,建议减轻体重,因为这至少在短期内可以缓解症状并减少药物治疗需求(B级建议)。(3)检测:(a)对于没有肥胖相关疾病的人,没有足够的证据建议将BMI测量纳入或排除在定期健康检查中,因此BMI测量由个体医疗保健提供者自行决定(C级建议);(b)对于患有肥胖相关疾病的人,建议进行BMI测量,因为当BMI超过27时应考虑减轻体重(B级建议)。
验证
加拿大预防保健工作组的成员通过反复过程对该分析的结果进行了审查。
资助者
加拿大预防保健工作组由省和地区卫生部与加拿大卫生部之间的合作提供资金。