Department of Anesthesiology and Critical Care, Higashi Omiya General Hospital, Saitama, Japan.
J Clin Monit Comput. 2011 Oct;25(5):323-8. doi: 10.1007/s10877-011-9311-3. Epub 2011 Oct 19.
For transcutaneous carbon dioxide pressure (tcPCO(2)) measurement, the probe on the trunk or extremities has been used for many years. Our previous study showed that chest was better than arm for tcPCO(2) monitoring. Recently, the ear probe has been developed. The accuracy of tcPCO(2) as a surrogate measurement of arterial carbon dioxide pressure (PaCO(2)) has not been compared between the measurement with probe on the chest and measurement with probe on the earlobe. This study compared the accuracy of tcPCO(2) measured on the chest and tcPCO(2) measured on earlobe during general anesthesia in adults using linear regression analysis and Bland-Altman plot.
Ten patients aged 30-70 years scheduled for abdominal surgery under general anesthesia were enrolled. TcPCO(2) by TCM4™ (Radiometer, Copenhagen, Denmark, TtcPCO(2)) with its probe on the chest, tcPCO(2) by Sentec™ (Sentec AG, Therwil, Switzerland, StcPCO(2)) with ear probe, end-tidal carbon dioxide pressure (EtCO(2)), and PaCO(2) were simultaneously measured at four different sets of EtCO(2) levels in each patient. In total, 40 measurements were performed. The Scatter plot and Bland-Altman plot were obtained. Correlation coefficient (R(2)) ≥0.70 and limits of agreement ≤4 mmHg were judged as significant.
TtcPCO(2) showed significant positive correlation with PaCO(2) (R(2) = 0.80) but StcPCO(2) did not (R(2) = 0.55). TtcPCO(2) and PaCO(2), and StcPCO(2) and PaCO(2) had large limits of agreement (-6.56 mmHg, 4.21 mmHg and -11.05 mmHg, 7.64 mmHg, respectively). TtcPCO(2) and StcPCO(2) had no significant correlation (R(2) = 0.63) and large limits of agreement (-8.98 mmHg to 7.91 mmHg).
During general anesthesia in adults, both TtcPCO(2) and StcPCO(2) were not interchangeable with PaCO(2), but only TtcPCO(2) had good positive correlation with PaCO(2).
对于经皮二氧化碳压力(tcPCO(2))测量,多年来一直使用躯干或四肢上的探头。我们之前的研究表明,胸部比手臂更适合 tcPCO(2)监测。最近,已经开发出了耳探头。 tcPCO(2)作为动脉二氧化碳压力(PaCO(2))替代测量值的准确性,尚未在胸部探头测量与耳垂探头测量之间进行比较。本研究使用线性回归分析和 Bland-Altman 图比较了全身麻醉成人中胸部 tcPCO(2)和耳垂 tcPCO(2)的准确性。
纳入 10 名年龄在 30-70 岁之间、拟行全身麻醉下腹部手术的患者。同时测量了使用 TCM4™(丹麦哥本哈根的 Radiometer,TtcPCO(2))胸部探头、使用 Sentec™(瑞士 Therwil 的 Sentec AG,StcPCO(2))耳探头的 tcPCO(2)、呼气末二氧化碳分压(EtCO(2))和 PaCO(2)。在每个患者的四个不同的 EtCO(2)水平集上进行了 40 次测量。获得了散点图和 Bland-Altman 图。判断相关系数(R(2))≥0.70 和一致性界限≤4mmHg 为有意义。
TtcPCO(2)与 PaCO(2)呈显著正相关(R(2)为 0.80),但 StcPCO(2) 无显著相关性(R(2)为 0.55)。 TtcPCO(2)和 PaCO(2)以及 StcPCO(2)和 PaCO(2)的一致性界限较大(分别为-6.56mmHg,4.21mmHg 和-11.05mmHg,7.64mmHg)。 TtcPCO(2)和 StcPCO(2)无显著相关性(R(2)为 0.63)且一致性界限较大(-8.98mmHg 至 7.91mmHg)。
在全身麻醉的成年人中, TtcPCO(2)和 StcPCO(2)均不能与 PaCO(2)互换,但只有 TtcPCO(2)与 PaCO(2)呈良好的正相关。